Literature DB >> 30439440

Tetrodotoxin and its analogues profile in nemertean species from the sea of Japan.

A E Vlasenko1, P V Velansky1, A V Chernyshev2, V G Kuznetsov3, T Yu Magarlamov4.   

Abstract

For the first time search for tetrodotoxin (TTX) and its analogues in the extracts of nemerteans using HPLC-MS/MS was performed. TTX analogues were detected in two nemertean species in addition to TTX: 7 analogues were detected in the extract of Cephalothrix simula, 3 analogues - in the extract 11-norTTX of Kulikovia manchenkoi. Presence of 5-deoxyTTX, 11-deoxyTTX, 5,6,11-trideoxyTTX and -6(R)-ol in nemerteans was shown for the first time.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  HPLC-MS/MS; Nemerteans; TTX; Tetrodotoxin; Tetrodotoxin analogues

Mesh:

Substances:

Year:  2018        PMID: 30439440     DOI: 10.1016/j.toxicon.2018.11.006

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  9 in total

Review 1.  The Toxins of Nemertean Worms.

Authors:  Ulf Göransson; Erik Jacobsson; Malin Strand; Håkan S Andersson
Journal:  Toxins (Basel)       Date:  2019-02-15       Impact factor: 4.546

2.  Stable Tetrodotoxin Production by Bacillus sp. Strain 1839.

Authors:  Daria I Melnikova; Anna E Vlasenko; Timur Yu Magarlamov
Journal:  Mar Drugs       Date:  2019-12-13       Impact factor: 5.118

3.  Tetrodotoxin and Its Analogues in Cephalothrix cf. simula (Nemertea: Palaeonemertea) from the Sea of Japan (Peter the Great Gulf): Intrabody Distribution and Secretions.

Authors:  Anna E Vlasenko; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2020-11-26       Impact factor: 4.546

4.  Investigation of Peptide Toxin Diversity in Ribbon Worms (Nemertea) Using a Transcriptomic Approach.

Authors:  Anna E Vlasenko; Vasiliy G Kuznetsov; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2022-08-08       Impact factor: 5.075

Review 5.  An Overview of the Anatomical Distribution of Tetrodotoxin in Animals.

Authors:  Daria I Melnikova; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2022-08-22       Impact factor: 5.075

6.  Novel Polyclonal Antibody Raised against Tetrodotoxin Using Its Haptenic Antigen Prepared from 4,9-anhydrotetrodotoxin Reacted with 1,2-Ethaneditiol and Further Reacted with Keyhole Limpet Hemocyanin.

Authors:  Shigeru Sato; Suzuka Takaishi; Ko Yasumoto; Shugo Watabe
Journal:  Toxins (Basel)       Date:  2019-09-20       Impact factor: 4.546

7.  The Microbial Community of Tetrodotoxin-Bearing and Non-Tetrodotoxin-Bearing Ribbon Worms (Nemertea) from the Sea of Japan.

Authors:  Daria I Melnikova; Timur Yu Magarlamov
Journal:  Mar Drugs       Date:  2020-03-23       Impact factor: 5.118

8.  Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea).

Authors:  Anna E Vlasenko; Vasiliy G Kuznetsov; Grigorii V Malykin; Alexandra O Pereverzeva; Peter V Velansky; Konstantin V Yakovlev; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2021-08-29       Impact factor: 4.546

9.  Intrabody Tetrodotoxin Distribution and Possible Hypothesis for Its Migration in Ribbon Worms Cephalothrix cf. simula (Palaeonemertea, Nemertea).

Authors:  Grigorii V Malykin; Alexei V Chernyshev; Timur Yu Magarlamov
Journal:  Mar Drugs       Date:  2021-08-29       Impact factor: 5.118

  9 in total

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