| Literature DB >> 30439440 |
A E Vlasenko1, P V Velansky1, A V Chernyshev2, V G Kuznetsov3, T Yu Magarlamov4.
Abstract
For the first time search for tetrodotoxin (TTX) and its analogues in the extracts of nemerteans using HPLC-MS/MS was performed. TTX analogues were detected in two nemertean species in addition to TTX: 7 analogues were detected in the extract of Cephalothrix simula, 3 analogues - in the extract 11-norTTX of Kulikovia manchenkoi. Presence of 5-deoxyTTX, 11-deoxyTTX, 5,6,11-trideoxyTTX and -6(R)-ol in nemerteans was shown for the first time.Entities:
Keywords: HPLC-MS/MS; Nemerteans; TTX; Tetrodotoxin; Tetrodotoxin analogues
Mesh:
Substances:
Year: 2018 PMID: 30439440 DOI: 10.1016/j.toxicon.2018.11.006
Source DB: PubMed Journal: Toxicon ISSN: 0041-0101 Impact factor: 3.033