Literature DB >> 3043005

Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionator.

B Pakkenberg1, H J Gundersen.   

Abstract

Unbiased estimates of the total number of neurons and glial cells from central regions of grey matter in human brains are obtained using the disector principle in modifications which are unaffected by the histological processing of paraffin-embedded tissue. Section thickness does not enter into the estimator and need not be known. An analysis of the contributions from all sampling levels to the variance of the estimator of total cell number has been used to design an optimimal sampling scheme. Using this method, a precise and unbiased estimate of the total number of neurons in a defined brain region can be obtained in less than 1 h.

Entities:  

Mesh：

Year:  1988        PMID： 3043005     DOI： 10.1111/j.1365-2818.1988.tb04582.x

Source DB:  PubMed          Journal:  J Microsc        ISSN： 0022-2720            Impact factor:   1.758


  64 in total

1.  Application of the fractionator and vertical slices to estimate total capillary length in skeletal muscle.

Authors:  E Artacho-Pérula; R Roldán-Villalobos; L M Cruz-Orive
Journal:  J Anat       Date:  1999-10       Impact factor: 2.610

2.  Neuron numbers in the hypothalamus of the normal aging rhesus monkey: stability across the adult lifespan and between the sexes.

Authors:  D E Roberts; R J Killiany; D L Rosene
Journal:  J Comp Neurol       Date:  2012-04-15       Impact factor: 3.215

3.  Quantitative analysis of neurons and glial cells in the rat somatosensory cortex, with special reference to GABAergic neurons and parvalbumin-containing neurons.

Authors:  J Q Ren; Y Aika; C W Heizmann; T Kosaka
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

Review 4.  The use of design-based stereology to evaluate volumes and numbers in the liver: a review with practical guidelines.

Authors:  Ricardo Marcos; Rogério A F Monteiro; Eduardo Rocha
Journal:  J Anat       Date:  2012-02-01       Impact factor: 2.610

5.  Proceedings of the Anatomical Society of Great Britain and Ireland. Papers presented at the symposium on Multidimensional Morphology Analysis held during the summer meeting of the Society. 11-13 July 1989, Liverpool. Abstracts.

Authors: 
Journal:  J Anat       Date:  1990-06       Impact factor: 2.610

6.  Fractionator studies on Purkinje cells in the human cerebellum: numbers in right and left halves of male and female brains.

Authors:  T M Mayhew; R MacLaren; C C Henery
Journal:  J Anat       Date:  1990-04       Impact factor: 2.610

7.  Comparative morphometry of the mammalian brain: estimates of cerebral volumes and cortical surface areas obtained from macroscopic slices.

Authors:  T M Mayhew; G L Mwamengele; V Dantzer
Journal:  J Anat       Date:  1990-10       Impact factor: 2.610

8.  The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method.

Authors:  B Pakkenberg; A Møller; H J Gundersen; A Mouritzen Dam; H Pakkenberg
Journal:  J Neurol Neurosurg Psychiatry       Date:  1991-01       Impact factor: 10.154

9.  The cerebrum and cerebellum of the fixed human brain: efficient and unbiased estimates of volumes and cortical surface areas.

Authors:  C C Henery; T M Mayhew
Journal:  J Anat       Date:  1989-12       Impact factor: 2.610

10.  Characterization of growth, glomerular number, and tubular proteins in the developing rhesus monkey kidney.

Authors:  Cynthia A Batchelder; Jennifer L Keyser; C Chang I Lee; Alice F Tarantal
Journal:  Anat Rec (Hoboken)       Date:  2013-09-02       Impact factor: 2.064
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.