Literature DB >> 30428730

Retrospective analysis of indications for termination of pregnancy.

Ozgur Ozyuncu1, Gokcen Orgul1, Atakan Tanacan1, Fatih Aktoz1, Naz Guleray2, Erdem Fadiloglu1, Mehmet Sinan Beksac1.   

Abstract

This is a retrospective study of 139 termination of pregnancies (TOPs) between November 2015 and November 2017 to demonstrate the indications. We have shown that 60.4%, 34.5% and 5% of the terminations were performed because of genetic disorders, foetal or obstetrical problems, and maternal causes, respectively. Congenital abnormalities (43.8%), anhydramniosis (17.2%) and chromosomal abnormalities (15.1%) were the most frequent causes of the TOPs. The central nervous system seemed to be the most frequent indicator found in our study. The critical finding is the presence of nine (6.4%) terminations because of foetal reasons beyond the 24th gestational week. A vaginal termination occurred in 91.4% of cases, whereas a hysterotomy was performed in 8.6% of the cases. Previous uterine surgery was the most significant risk factor for a hysterotomy. Knowing the foetal indications is essential to know the aetiological and medico-legal backgrounds of the TOPs for better planning and medical counselling. Impact statement What is already known on this subject? Congenital anomalies are most common cause of termination of wanted pregnancies. Terminations beyond 24 weeks are also evaluated as unethical and create an ethical concern. The legal limitations differ between countries in terms of the legal limit in pregnancy for terminations. What do the results of this study add? We have demonstrated the congenital anomalies are the most common reason for pregnancy terminations after excluding fetal demise and unwanted pregnancies. We also showed that congenital anomalies and chromosomal abnormalities are most common indications for terminations of pregnancies beyond 24 weeks. The legal arrangements related to the termination of pregnancies in Turkey are described. Prior uterine surgery is a significant risk factor for hysterotomies in the termination of pregnancies. What are the implications of these findings for clinical practice and/or further research? It is critical to know the aetiological background of termination of pregnancies for better planning and consultation.

Entities:  

Keywords:  Termination of pregnancy; congenital anomalies; foetal indications; prenatal diagnosis

Mesh:

Year:  2018        PMID: 30428730     DOI: 10.1080/01443615.2018.1506427

Source DB:  PubMed          Journal:  J Obstet Gynaecol        ISSN: 0144-3615            Impact factor:   1.246


  4 in total

Review 1.  Perinatal post-mortem ultrasound (PMUS): radiological-pathological correlation.

Authors:  Susan C Shelmerdine; Neil J Sebire; Owen J Arthurs
Journal:  Insights Imaging       Date:  2019-08-21

2.  Clinical Course and Outcome of Non-Immune Fetal Hydrops in Singleton Pregnancies.

Authors:  Theresa Reischer; Bernadette Muth; Anja Catic; Cécile Monod; Tina Linder; Christian Göbl; Gülen Yerlikaya-Schatten
Journal:  J Clin Med       Date:  2022-01-28       Impact factor: 4.241

3.  Retrospective clinical evaluation of indications for termination of pregnancies due to fetal anomaly

Authors:  Özlem Koşar Can; Babür Kaleli
Journal:  J Turk Ger Gynecol Assoc       Date:  2022-03-08

Review 4.  Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review.

Authors:  Carlos Pérez-Serrano; Álvaro Bartolomé; Núria Bargalló; Carmen Sebastià; Alfons Nadal; Olga Gómez; Laura Oleaga
Journal:  Insights Imaging       Date:  2021-07-22
  4 in total

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