Literature DB >> 30426891

Current Scenario in Structure and Ligand-Based Drug Design on Anti-colon Cancer Drugs.

Lakshmanan Loganathan1, Karthikeyan Muthusamy1.   

Abstract

Worldwide, colorectal cancer takes up the third position in commonly detected cancer and fourth in cancer mortality. Recent progress in molecular modeling studies has led to significant success in drug discovery using structure and ligand-based methods. This study highlights aspects of the anticancer drug design. The structure and ligand-based drug design are discussed to investigate the molecular and quantum mechanics in anti-cancer drugs. Recent advances in anticancer agent identification driven by structural and molecular insights are presented. As a result, the recent advances in the field and the current scenario in drug designing of cancer drugs are discussed. This review provides information on how cancer drugs were formulated and identified using computational power by the drug discovery society. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Keywords:  Colorectal cancer; anti-colon cancer drugs; chronic degenerative diseasezzm321990(CDD); drug designing; structure-ligand based screening.

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Year:  2018        PMID: 30426891     DOI: 10.2174/1381612824666181114114513

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  1 in total

1.  Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion.

Authors:  Jinling Bi; Yong Huang; Yulong Liu
Journal:  Transl Cancer Res       Date:  2019-10       Impact factor: 1.241

  1 in total

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