| Literature DB >> 30426391 |
Zahra Eskandani1,2, Tony Le Gall3,4, Tristan Montier3,4,5,6, Pierre Lehn3, Fabien Montel7, Loïc Auvray7, Cécile Huin1,2, Philippe Guégan8.
Abstract
Symmetrical cyclodextrin-based 14-arm star polymers with poly(ethylene glycol) PEG branches were synthesized and characterized. Interactions of the star polymers with lipid bilayers were studied by the "black lipid membrane" technique in order to demonstrate the formation of monomolecular artificial channels. The conditions for the insertion are mainly based on dimensions and amphiphilic properties of the star polymers, in particular the molar mass of the water-soluble polymer branches. Translocation of single-strand DNA (ssDNA) through those synthetic nanopores was investigated, and the close dimension between the cross-section of ssDNA and the cyclodextrin cavity led to an energy barrier that slowed down the translocation process.Entities:
Keywords: Polymers: From Adsorption to Translocation - Topical Issue in Memoriam Loïc Auvray (1956-2016)
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Year: 2018 PMID： 30426391 DOI： 10.1140/epje/i2018-11743-3
Source DB: PubMed Journal: Eur Phys J E Soft Matter ISSN： 1292-8941 Impact factor: 1.890