Literature DB >> 30425355

Increased synthesis of a coenzyme linked to longevity can combat disease.

Samir M Parikh.   

Abstract

Keywords:  Diseases; Metabolism; Physiology

Mesh：

Substances：

Year:  2018        PMID： 30425355     DOI： 10.1038/d41586-018-07088-4

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  14 in total

1.  Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.

Authors:  Ling Liu; Xiaoyang Su; William J Quinn; Sheng Hui; Kristin Krukenberg; David W Frederick; Philip Redpath; Le Zhan; Karthikeyani Chellappa; Eileen White; Marie Migaud; Timothy J Mitchison; Joseph A Baur; Joshua D Rabinowitz
Journal:  Cell Metab       Date:  2018-05-01       Impact factor: 27.287

2.  NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

Authors:  Hongjun Shi; Annabelle Enriquez; Melissa Rapadas; Ella M M A Martin; Roni Wang; Julie Moreau; Chai K Lim; Justin O Szot; Eddie Ip; James N Hughes; Kotaro Sugimoto; David T Humphreys; Aideen M McInerney-Leo; Paul J Leo; Ghassan J Maghzal; Jake Halliday; Janine Smith; Alison Colley; Paul R Mark; Felicity Collins; David O Sillence; David S Winlaw; Joshua W K Ho; Gilles J Guillemin; Matthew A Brown; Kazu Kikuchi; Paul Q Thomas; Roland Stocker; Eleni Giannoulatou; Gavin Chapman; Emma L Duncan; Duncan B Sparrow; Sally L Dunwoodie
Journal:  N Engl J Med       Date:  2017-08-10       Impact factor: 91.245

3.  Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis".

Authors:  Shin-Ichi Fukuoka; Kanako Ishiguro; Kazumi Yanagihara; Atsushi Tanabe; Yukari Egashira; Hiroo Sanada; Katsumi Shibata
Journal:  J Biol Chem       Date:  2002-07-24       Impact factor: 5.157

4.  Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism.

Authors:  Lisa Pucci; Silvia Perozzi; Flavio Cimadamore; Giuseppe Orsomando; Nadia Raffaelli
Journal:  FEBS J       Date:  2007-02       Impact factor: 5.542

5.  Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Authors:  Ana P Gomes; Nathan L Price; Alvin J Y Ling; Javid J Moslehi; Magdalene K Montgomery; Luis Rajman; James P White; João S Teodoro; Christiane D Wrann; Basil P Hubbard; Evi M Mercken; Carlos M Palmeira; Rafael de Cabo; Anabela P Rolo; Nigel Turner; Eric L Bell; David A Sinclair
Journal:  Cell       Date:  2013-12-19       Impact factor: 41.582

6.  GROWTH-RETARDING EFFECT OF CORN IN NICOTINIC ACID-LOW RATIONS AND ITS COUNTERACTION BY TRYPTOPHANE.

Authors:  W A Krehl; L J Teply; P S Sarma; C A Elvehjem
Journal:  Science       Date:  1945-05-11       Impact factor: 47.728

7.  Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.

Authors:  Karim Gariani; Keir J Menzies; Dongryeol Ryu; Casey J Wegner; Xu Wang; Eduardo R Ropelle; Norman Moullan; Hongbo Zhang; Alessia Perino; Vera Lemos; Bohkyung Kim; Young-Ki Park; Alessandra Piersigilli; Tho X Pham; Yue Yang; Chai Siah Ku; Sung I Koo; Anna Fomitchova; Carlos Cantó; Kristina Schoonjans; Anthony A Sauve; Ji-Young Lee; Johan Auwerx
Journal:  Hepatology       Date:  2015-12-16       Impact factor: 17.425

8.  PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.

Authors:  Mei T Tran; Zsuzsanna K Zsengeller; Anders H Berg; Eliyahu V Khankin; Manoj K Bhasin; Wondong Kim; Clary B Clish; Isaac E Stillman; S Ananth Karumanchi; Eugene P Rhee; Samir M Parikh
Journal:  Nature       Date:  2016-03-16       Impact factor: 49.962

9.  De novo NAD+ biosynthetic impairment in acute kidney injury in humans.

Authors:  Ali Poyan Mehr; Mei T Tran; Kenneth M Ralto; David E Leaf; Vaughan Washco; Joseph Messmer; Adam Lerner; Ajay Kher; Steven H Kim; Charbel C Khoury; Shoshana J Herzig; Mary E Trovato; Noemie Simon-Tillaux; Matthew R Lynch; Ravi I Thadhani; Clary B Clish; Kamal R Khabbaz; Eugene P Rhee; Sushrut S Waikar; Anders H Berg; Samir M Parikh
Journal:  Nat Med       Date:  2018-08-20       Impact factor: 53.440

10.  The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Authors:  Laurent Mouchiroud; Riekelt H Houtkooper; Norman Moullan; Elena Katsyuba; Dongryeol Ryu; Carles Cantó; Adrienne Mottis; Young-Suk Jo; Mohan Viswanathan; Kristina Schoonjans; Leonard Guarente; Johan Auwerx
Journal:  Cell       Date:  2013-07-18       Impact factor: 41.582
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