Literature DB >> 30422908

Impact of Home-Based HIV Testing Services on Progress Toward the UNAIDS 90-90-90 Targets in a Hyperendemic Area of South Africa.

Lara Lewis1, Brendan Maughan-Brown2, Anneke Grobler1,3, Cherie Cawood4, David Khanyile4, Mary Glenshaw5, Ayesha B M Kharsany1.   

Abstract

BACKGROUND: In several subgroups of South Africa, the percentage of HIV-positive individuals aware of their status falls well below the UNAIDS 90% target. This study examined the impact that home-based HIV testing services (HBHTS) had on knowledge of status in a hyperendemic area of South Africa.
METHODS: We analysed data from the second cross-sectional HIV Incidence Provincial Surveillance System survey (2015/2016), a representative sample (n = 10,236) of individuals aged 15-49 years. Participants completed a questionnaire, provided blood samples for laboratory testing (used to estimate HIV prevalence), and were offered HBHTS. The proportion of people living with HIV (n = 3870) made aware of their status through HBHTS was measured, and factors associated with HBHTS uptake were identified.
RESULTS: Knowledge of HIV-positive status at the time of the survey was 62.9% among men and 73.4% among women. Through HBHTS, the percentage of HIV-positive men and women who knew their status rose to 74.2% and 80.5%, respectively. The largest impact was observed among youth (15-24 years). Knowledge of status increased from 36.6% to 59.3% and from 50.8% to 64.8% among young men and women, respectively. In addition, 51.4% of those who had previously never tested received their first test. Key reasons for declining HBHTS among undiagnosed HIV-positive individuals included fear and self-report of an HIV-negative status.
CONCLUSIONS: HBHTS was effective in increasing awareness of HIV-positive status, particularly among youth, men, and those who had never tested. HBHTS could have a marked impact on progress toward the UNAIDS 90-90-90 targets within these subgroups.

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Year:  2019        PMID: 30422908      PMCID: PMC6331263          DOI: 10.1097/QAI.0000000000001900

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  22 in total

1.  Correcting HIV prevalence estimates for survey nonparticipation using Heckman-type selection models.

Authors:  Till Bärnighausen; Jacob Bor; Speciosa Wandira-Kazibwe; David Canning
Journal:  Epidemiology       Date:  2011-01       Impact factor: 4.822

2.  Who gets tested for HIV in a South African urban township? Implications for test and treat and gender-based prevention interventions.

Authors:  Kartik K Venkatesh; Precious Madiba; Guy De Bruyn; Mark N Lurie; Thomas J Coates; Glenda E Gray
Journal:  J Acquir Immune Defic Syndr       Date:  2011-02-01       Impact factor: 3.731

3.  Rates of HIV testing and diagnosis in South Africa: successes and challenges.

Authors:  Leigh F Johnson; Thomas M Rehle; Sean Jooste; Linda-Gail Bekker
Journal:  AIDS       Date:  2015-07-17       Impact factor: 4.177

4.  An incentivized HIV counseling and testing program targeting hard-to-reach unemployed men in Cape Town, South Africa.

Authors:  Mweete D Nglazi; Nienke van Schaik; Katharina Kranzer; Stephen D Lawn; Robin Wood; Linda-Gail Bekker
Journal:  J Acquir Immune Defic Syndr       Date:  2012-03-01       Impact factor: 3.731

Review 5.  Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa.

Authors:  Monisha Sharma; Roger Ying; Gillian Tarr; Ruanne Barnabas
Journal:  Nature       Date:  2015-12-03       Impact factor: 49.962

6.  Misdiagnosis of HIV infection during a South African community-based survey: implications for rapid HIV testing.

Authors:  Tendesayi Kufa; Ayesha Bm Kharsany; Cherie Cawood; David Khanyile; Lara Lewis; Anneke Grobler; Zawadi Chipeta; Alfred Bere; Mary Glenshaw; Adrian Puren
Journal:  J Int AIDS Soc       Date:  2017-08-29       Impact factor: 5.396

Review 7.  Uptake of home-based voluntary HIV testing in sub-Saharan Africa: a systematic review and meta-analysis.

Authors:  Kalpana Sabapathy; Rafael Van den Bergh; Sarah Fidler; Richard Hayes; Nathan Ford
Journal:  PLoS Med       Date:  2012-12-04       Impact factor: 11.069

8.  Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa.

Authors:  Ayesha B M Kharsany; Cherie Cawood; David Khanyile; Anneke Grobler; Lyle R Mckinnon; Natasha Samsunder; Janet A Frohlich; Quarraisha Abdool Karim; Adrian Puren; Alex Welte; Gavin George; Kaymarlin Govender; Carlos Toledo; Zawadi Chipeta; Lycias Zembe; Mary T Glenshaw; Lorna Madurai; Varough M Deyde; Alfred Bere
Journal:  BMC Public Health       Date:  2015-11-20       Impact factor: 3.295

9.  Linkage to care following a home-based HIV counselling and testing intervention in rural South Africa.

Authors:  Reshma Naik; Tanya Doherty; Debra Jackson; Hanani Tabana; Sonja Swanevelder; Donald M Thea; Frank G Feeley; Matthew P Fox
Journal:  J Int AIDS Soc       Date:  2015-06-08       Impact factor: 5.396

10.  Adjusting HIV prevalence estimates for non-participation: an application to demographic surveillance.

Authors:  Mark E McGovern; Giampiero Marra; Rosalba Radice; David Canning; Marie-Louise Newell; Till Bärnighausen
Journal:  J Int AIDS Soc       Date:  2015-11-26       Impact factor: 5.396

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1.  "I got tested at home, the help came to me": acceptability and feasibility of home-based TB testing of household contacts using portable molecular diagnostics in South Africa.

Authors:  Andrew Medina-Marino; Lindsey de Vos; Dana Bezuidenhout; Claudia M Denkinger; Samuel G Schumacher; Sanghyuk S Shin; Wendy Stevens; Grant Theron; Martie van der Walt; Joseph Daniels
Journal:  Trop Med Int Health       Date:  2021-01-04       Impact factor: 2.622

2.  Home-based HIV Testing for Children: A Useful Complement for Caregivers with More Children, Who are Male, and with an HIV Negative Partner.

Authors:  Jiayu Wang; Cyrus Mugo; Vincent O Omondi; Irene N Njuguna; Elizabeth Maleche-Obimbo; Irene Inwani; James P Hughes; Jennifer A Slyker; Grace John-Stewart; Dalton Wamalwa; Anjuli D Wagner
Journal:  AIDS Behav       Date:  2022-03-19

3.  Poor rates of linkage to HIV care and uptake of treatment after home-based HIV testing among newly diagnosed 15-to-49 year-old men and women in a high HIV prevalence setting in South Africa.

Authors:  Brendan Maughan-Brown; Sean Beckett; Ayesha B M Kharsany; Cherie Cawood; David Khanyile; Lara Lewis; Atheendar Venkataramani; Gavin George
Journal:  AIDS Care       Date:  2020-02-09

4.  Baseline CD4 and mortality trends in the South African human immunodeficiency virus programme: Analysis of routine data.

Authors:  Rivka R Lilian; Kate Rees; Moyahabo Mabitsi; James A McIntyre; Helen E Struthers; Remco P H Peters
Journal:  South Afr J HIV Med       Date:  2019-07-24       Impact factor: 2.744

5.  Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States.

Authors:  Karine Dubé; Shadi Eskaf; Elizabeth Hastie; Harsh Agarwal; Laney Henley; Christopher Roebuck; William B Carter; Lynda Dee; Jeff Taylor; Derrick Mapp; Danielle M Campbell; Thomas J Villa; Beth Peterson; Kenneth M Lynn; Linden Lalley-Chareczko; Emily Hiserodt; Sukyung Kim; Daniel Rosenbloom; Brad R Evans; Melanie Anderson; Daria J Hazuda; Lisa Shipley; Kevin Bateman; Bonnie J Howell; Karam Mounzer; Pablo Tebas; Luis J Montaner
Journal:  J Pers Med       Date:  2022-02-07

6.  Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa.

Authors:  Niklaus Daniel Labhardt; Isaac Ringera; Thabo Ishmael Lejone; Alain Amstutz; Thomas Klimkait; Josephine Muhairwe; Tracy Renee Glass
Journal:  BMC Public Health       Date:  2019-11-01       Impact factor: 3.295

7.  Impact of a community-wide combination HIV prevention intervention on knowledge of HIV status among adolescents.

Authors:  Kwame Shanaube; Ab Schaap; Graeme Hoddinott; Constance Mubekapi-Musadaidzwa; Sian Floyd; Peter Bock; Richard Hayes; Sarah Fidler; Helen Ayles
Journal:  AIDS       Date:  2021-02-02       Impact factor: 4.632

Review 8.  Men missing from the HIV care continuum in sub-Saharan Africa: a meta-analysis and meta-synthesis.

Authors:  Maria F Nardell; Oluwatomi Adeoti; Carson Peters; Bernard Kakuhikire; Caroline Govathson-Mandimika; Lawrence Long; Sophie Pascoe; Alexander C Tsai; Ingrid T Katz
Journal:  J Int AIDS Soc       Date:  2022-03       Impact factor: 5.396

  8 in total

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