Literature DB >> 30422049

Development of Secondary Choroidal Neovascularization in Focal Choroidal Excavation of Punctate Inner Choroidopathy.

Anna-Maria Haas1, Martin Stattin1,2, Daniel Ahmed1,2, Ilse Krebs1,2, Siamak Ansari-Shahrezaei1,2,3.   

Abstract

Purpose: To elaborate a case of focal choroidal excavation (FCE) in punctate inner choroidopathy (PIC) complicated by secondary choroidal neovascularization (CNV) based on multimodal imaging findings.
Methods: In this retrospective case report, multimodal imaging including near-infrared reflectance, blue peak autofluorescence, spectral domain-optical coherence tomography (OCT), fluorescein and indocyanine green angiography (Heidelberg Engineering GmbH, Germany), and swept source-OCT angiography (SS-OCTA; Topcon Corporation, Japan) was performed.Patients: A 27-year-old moderate myopic woman presented with inactive CNV of unknown origin in her left eye, which had been previously treated with intravitreal anti-vascular endothelial growth factor.
Results: Multimodal imaging revealed PIC as the causative disease and systemic corticosteroids were administered. Similar complaints 13 months later showed new CNV formation at the already documented FCE. No sign of PIC could be detected at follow-up.
Conclusion: This well-documented case highlighted FCE as the preferential location for CNV development in PIC with multimodal imaging emphasizing a chorioretinal entity.Summary: This case report demonstrated the clinical course of focal choroidal excavation in a patient initially diagnosed with punctate inner choroidopathy complicated by choroidal neovascularization and its treatment response, well documented by multimodal imaging including optical coherence tomography angiography.

Entities:  

Keywords:  Choroidal neovascularization; focal choroidal excavation; punctate inner choroidopathy; swept source-optical coherence tomography angiography

Mesh:

Year:  2018        PMID: 30422049     DOI: 10.1080/09273948.2018.1540708

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  5 in total

1.  Focal choroidal excavation complicated with choroidal neovascularization: a case report and review of the literature.

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2.  Establishing a mouse model of choroidal neovascularization to study the therapeutic effect of levotinib and its mechanism.

Authors:  Xiaonan Xin; Yueyu Zhu; Ruijie Xi; Yuhua Hao
Journal:  Saudi J Biol Sci       Date:  2020-06-27       Impact factor: 4.219

3.  Clinical Study of Intravitreal Injection of Anti-VEGF Drugs Combined with Triamcinolone Acetonide in the Treatment of Coats Disease.

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4.  Assessment of conbercept therapy for high myopia macular neovascularization by optical coherence tomography angiography.

Authors:  Lu-Na Cheng; Yu-Xi Lin; Lei Liu; Xu-He Zhang; Yan-Qi Xue; Sheng-Di Zhou; Zhe-Li Liu; Han Zhang
Journal:  Sci Rep       Date:  2020-10-12       Impact factor: 4.379

5.  Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization.

Authors:  Rui Gao; Jingxue Ma; Zhengwei Zhang; Qingli Shang; Jialiang Duan
Journal:  Ann Med       Date:  2021-12       Impact factor: 4.709

  5 in total

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