Literature DB >> 30421308

Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials.

Sameh Hany Emile1, Hossam Elfeki2,3, Ahmad Sakr2,4, Mostafa Shalaby2.   

Abstract

BACKGROUND: Although conventional hemorrhoidectomy proved effective in treatment of hemorrhoidal disease, postoperative pain remains a vexing problem. Alternatives to conventional hemorrhoidectomy as transanal hemorrhoidal dearterialization (THD) and stapled hemorrhoidopexy (SH) were described. The present meta-analysis aimed to review the randomized trials that compared THD and SH to determine which technique is superior in terms of recurrence of hemorrhoids, complications, and postoperative pain.
METHODS: Electronic databases were searched for randomized trials that compared THD and SH for internal hemorrhoids. The PRISMA guidelines were followed when reporting this meta-analysis. The primary endpoint of the analysis was persistence or recurrence of hemorrhoidal disease. Secondary endpoints were postoperative pain, complications, readmission, return to work, and patients' satisfaction.
RESULTS: Six randomized trials including 554 patients (THD = 280; SH = 274) were included. The mean postoperative pain score of THD was significantly lower than SH (2.9 ± 1.5 versus 3.3 ± 1.6). 13.2% of patients experienced persistent or recurrent hemorrhoids after THD versus 6.9% after SH (OR = 1.93, 95%CI = 1.07-3.51, p = 0.029). Complications were recorded in 17.1% of patients who underwent THD and 23.3% of patients who underwent SH (OR = 0.68, 95%CI 0.43-1.05, p = 0.08). The average duration to return to work after THD was 7.3 ± 5.2 versus 7.7 ± 4.8 days after SH (p = 0.34). Grade IV hemorrhoids was significantly associated with persistence or recurrence of hemorrhoidal disease after both procedures.
CONCLUSION: THD had significantly higher persistence/recurrence rate compared to SH whereas complication and readmission rates, hospital stay, return to work, and patients' satisfaction were similar in both groups.

Entities:  

Keywords:  Hemorrhoids; Meta-analysis; Randomized clinical trials; Stapled hemorrhoidopexy; Transanal hemorrhoidal dearterialization

Mesh:

Year:  2018        PMID: 30421308     DOI: 10.1007/s00384-018-3187-3

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  5 in total

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3.  Modified tissue-selecting therapy stapler combined with complete anal canal epithelial preservation operation for the treatment of circumferential mixed haemorrhoids: a protocol for single-blind randomised controlled study.

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Journal:  BMJ Open       Date:  2021-11-24       Impact factor: 2.692

4.  Management of haemorrhoids: protocol of an umbrella review of systematic reviews and meta-analyses.

Authors:  Min Chen; Tai-Chun Tang; Tao-Hong He; Yong-Jun Du; Di Qin; Hui Zheng
Journal:  BMJ Open       Date:  2020-03-25       Impact factor: 2.692

5.  Tissue selecting technique mega-window stapler combined with anal canal epithelial preservation operation for the treatment of severe prolapsed hemorrhoids: A study protocol for a randomized controlled trial.

Authors:  Lijiang Ji; Lei Li; Liping Weng; Yuemeng Hu; Hua Huang; Jun Wei
Journal:  Medicine (Baltimore)       Date:  2020-11-06       Impact factor: 1.817

  5 in total

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