Literature DB >> 30421234

Metabolomics Analysis of Leishmania by Capillary Electrophoresis and Mass Spectrometry.

David Rojo1, Coral Barbas1, Ángeles López-Gonzálvez2.   

Abstract

Capillary electrophoresis coupled to mass spectrometry is an analytical platform ideal for the analysis of ionic or polar metabolites. It constitutes a perfect complement to reversed-phase liquid chromatography, offering a good alternative to polar stationary phases where reproducibility is not guaranteed. Herein, we describe a robust standardized methodology for the fingerprinting analysis of Leishmania, a taxonomic genus which comprises more than 20 protozoa species.

Entities:  

Keywords:  Fingerprinting; Parasite phenotyping; Polar metabolites; Untargeted metabolomics

Mesh：

Year:  2019        PMID： 30421234     DOI： 10.1007/978-1-4939-8757-3_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  2 in total

1.  Metabolomic Profile of BALB/c Macrophages Infected with Leishmania amazonensis: Deciphering L-Arginine Metabolism.

Authors:  Sandra Marcia Muxel; Maricruz Mamani-Huanca; Juliana Ide Aoki; Ricardo Andrade Zampieri; Lucile Maria Floeter-Winter; Ángeles López-Gonzálvez; Coral Barbas
Journal:  Int J Mol Sci       Date:  2019-12-11       Impact factor: 5.923

2.  Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation.

Authors:  Nicolas Drouin; Marlien van Mever; Wei Zhang; Elena Tobolkina; Sabrina Ferre; Anne-Catherine Servais; Marie-Jia Gou; Laurent Nyssen; Marianne Fillet; Guinevere S M Lageveen-Kammeijer; Jan Nouta; Andrew J Chetwynd; Iseult Lynch; James A Thorn; Jens Meixner; Christopher Lößner; Myriam Taverna; Sylvie Liu; N Thuy Tran; Yannis Francois; Antony Lechner; Reine Nehmé; Ghassan Al Hamoui Dit Banni; Rouba Nasreddine; Cyril Colas; Herbert H Lindner; Klaus Faserl; Christian Neusüß; Manuel Nelke; Stefan Lämmerer; Catherine Perrin; Claudia Bich-Muracciole; Coral Barbas; Ángeles López Gonzálvez; Andras Guttman; Marton Szigeti; Philip Britz-McKibbin; Zachary Kroezen; Meera Shanmuganathan; Peter Nemes; Erika P Portero; Thomas Hankemeier; Santiago Codesido; Víctor González-Ruiz; Serge Rudaz; Rawi Ramautar
Journal:  Anal Chem       Date:  2020-10-01       Impact factor: 6.986
  2 in total

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