Optimizing testing for Clostridium difficile infection: A quality improvement project.

Overtesting for Clostridium difficile may result in increased health care facility-onset C difficile infection LabID events. Our quality improvement project optimized testing through standardization of laboratory processes, electronic health record clinical decision support, and real-time monitoring. Our intervention resulted in a 59% reduction in health care facility-onset C difficile infection LabID events.