Danqing Hu1, Lixiao Cheng1, Wenjie Jiang2. 1. Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, No. 38 Dengzhou Road, Qingdao, Shandong 266021, China. 2. Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, No. 38 Dengzhou Road, Qingdao, Shandong 266021, China. Electronic address: wenjie-jiang@qdu.edu.cn.
Abstract
BACKGROUND: It remains inconsistent whether sugar-sweetened beverages (SSBs) consumption increases the risk of depression. Thus, we carried out a meta-analysis to evaluate the association between SSBs consumption and the risk of depression. METHODS: PubMed and Web of Science were searched for relevant articles published up to June 2018. Pooled relative risks (RRs) and 95% confidence intervals (CIs) were calculated by the fixed-effects model or random effect model based on heterogeneity test. RESULTS: 10 observational studies involving 37,131 depression cases among 365,289 participants were included. The combined risk of depression for the highest versus lowest consumption of SSBs was 1.31 (95% CI 1.24-1.39). The findings were consistent in the cross-sectional studies (RR = 1.38; 95% CI 1.26-1.52) as well as in the cohort studies (RR = 1.30; 95% CI 1.19-1.41) A nonlinear dose-response relationship was found (Pnonlinearity = 0.0103) for depression risk and SSBs consumption. Compared with SSBs nondrinkers, those who drank the equivalent of 2 cups/day of cola might increase the risk of depression by 5% (RR = 1.05; 95% CI 1.01-1.09). And the equivalent of 3cans/day of cola might have approximately 25% higher risk of depression. LIMITATIONS: 10 studies were included in this meta-analysis, of which only 4 were cohort studies, and more cohort studies need to be performed in the future. CONCLUSIONS: This meta-analysis indicates that SSBs consumption might be associated with a modestly higher risk of depression. The results need to be further confirmed in the future.
BACKGROUND: It remains inconsistent whether sugar-sweetened beverages (SSBs) consumption increases the risk of depression. Thus, we carried out a meta-analysis to evaluate the association between SSBs consumption and the risk of depression. METHODS: PubMed and Web of Science were searched for relevant articles published up to June 2018. Pooled relative risks (RRs) and 95% confidence intervals (CIs) were calculated by the fixed-effects model or random effect model based on heterogeneity test. RESULTS: 10 observational studies involving 37,131 depression cases among 365,289 participants were included. The combined risk of depression for the highest versus lowest consumption of SSBs was 1.31 (95% CI 1.24-1.39). The findings were consistent in the cross-sectional studies (RR = 1.38; 95% CI 1.26-1.52) as well as in the cohort studies (RR = 1.30; 95% CI 1.19-1.41) A nonlinear dose-response relationship was found (Pnonlinearity = 0.0103) for depression risk and SSBs consumption. Compared with SSBs nondrinkers, those who drank the equivalent of 2 cups/day of cola might increase the risk of depression by 5% (RR = 1.05; 95% CI 1.01-1.09). And the equivalent of 3cans/day of cola might have approximately 25% higher risk of depression. LIMITATIONS: 10 studies were included in this meta-analysis, of which only 4 were cohort studies, and more cohort studies need to be performed in the future. CONCLUSIONS: This meta-analysis indicates that SSBs consumption might be associated with a modestly higher risk of depression. The results need to be further confirmed in the future.
Authors: Lale A Ertuglu; Baris Afsar; Abdullah B Yildiz; Atalay Demiray; Alberto Ortiz; Adrian Covic; Mehmet Kanbay Journal: Curr Nutr Rep Date: 2021-09-30
Authors: Joseph Firth; Marco Solmi; Robyn E Wootton; Davy Vancampfort; Felipe B Schuch; Erin Hoare; Simon Gilbody; John Torous; Scott B Teasdale; Sarah E Jackson; Lee Smith; Melissa Eaton; Felice N Jacka; Nicola Veronese; Wolfgang Marx; Garcia Ashdown-Franks; Dan Siskind; Jerome Sarris; Simon Rosenbaum; André F Carvalho; Brendon Stubbs Journal: World Psychiatry Date: 2020-10 Impact factor: 49.548
Authors: M Ángeles Pérez-Ara; Margalida Gili; Marjolein Visser; Brenda W J H Penninx; Ingeborg A Brouwer; Ed Watkins; Matt Owens; Mauro García-Toro; Ulrich Hegerl; Elisabeth Kohls; Mariska Bot; Miquel Roca Journal: Nutrients Date: 2020-10-20 Impact factor: 5.717