Griselda N Copa1,2, María C Almazán1,2, Lorena V Aramayo2, Alejandro J Krolewiecki1, Silvana P Cajal1, Marisa Juarez1, Juan J Lauthier3, Masataka Korenaga3, Paola Barroso4, Julio R Nasser1,2, Jorge D Marco4, José F Gil1,5. 1. Instituto de Investigaciones de Enfermedades Tropicales (IIET), Sede Regional Orán, Facultad de Ciencias de la Salud, Universidad Nacional de Salta. Alvarado 751 - San Ramón de la Nueva Orán-C.P.4530. 2. Cátedra de Química Biológica y Biología Molecular, Facultad de Ciencias Naturales, Universidad Nacional de Salta. Universidad Nacional de Salta. Av. Bolivia 5150 - CP. 3. Parasitology Department, Kochi Medical School, Kochi University, Oko, Nankoku, Kochi, Japan. 4. Instituto de Patología Experimental (IPE-CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de Salta. Av. Bolivia 5150 - CP. 5. Instituto de Investigación en Energía No Convencional (INENCO-CONICET), Departamento de Física, Universidad Nacional de Salta. Av. Bolivia 5150 - CP.
Abstract
Background: Some sand flies are of medical importance because they are vectors of Leishmania parasites that are responsible for leishmaniasis. The aim of this study was to make a retrospective epidemiological analysis of tegumentary leishmaniasis (TL), to identify Leishmania spp. from patient isolates and to describe the diversity of sand flies from a border area between Bolivia and Argentina. Methods: TL cases included in the study were diagnosed in an endemic area of the north of Argentina from 1985 to 2017. The parasites isolated were characterized by the cytochrome B method. Sand flies were captured with Centers for Disease Control traps in Aguas Blancas and Media Luna-Algarrobito localities. Results: A total of 118 cases of TL were analysed. Eight isolates were characterized as Leishmania (Viannia) braziliensis. A total of 1291 sand flies were captured, including Nyssomyia neivai, Cortelezzii complex, Evandromyia sallesi, Migonemyia migonei and Micropygomyia quinquefer. Within the area, sand flies were found in the backyards of houses. Conclusions: In this region there exists the possibility of peridomestic transmission of TL in the neighbourhoods peripheral to the urban area and in rural environments as well as the risk of transmission to travellers that pass through the customs offices.
Background: Some sand flies are of medical importance because they are vectors of Leishmania parasites that are responsible for leishmaniasis. The aim of this study was to make a retrospective epidemiological analysis of tegumentary leishmaniasis (TL), to identify Leishmania spp. from patient isolates and to describe the diversity of sand flies from a border area between Bolivia and Argentina. Methods: TL cases included in the study were diagnosed in an endemic area of the north of Argentina from 1985 to 2017. The parasites isolated were characterized by the cytochrome B method. Sand flies were captured with Centers for Disease Control traps in Aguas Blancas and Media Luna-Algarrobito localities. Results: A total of 118 cases of TL were analysed. Eight isolates were characterized as Leishmania (Viannia) braziliensis. A total of 1291 sand flies were captured, including Nyssomyia neivai, Cortelezzii complex, Evandromyia sallesi, Migonemyia migonei and Micropygomyia quinquefer. Within the area, sand flies were found in the backyards of houses. Conclusions: In this region there exists the possibility of peridomestic transmission of TL in the neighbourhoods peripheral to the urban area and in rural environments as well as the risk of transmission to travellers that pass through the customs offices.
Authors: María Gabriela Quintana; Angélica Pech-May; Ana Denise Fuenzalida; José Manuel Direni Mancini; Paola Andrea Barroso; Zaida Estela Yadón; Mario Zaidenberg; Oscar Daniel Salomón Journal: Mem Inst Oswaldo Cruz Date: 2019-09-30 Impact factor: 2.743