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Literature DB >> 30418047

IL-1 Blockade Reduces Inflammation in Pulmonary Arterial Hypertension and Right Ventricular Failure: A Single-Arm, Open-Label, Phase IB/II Pilot Study.

Cory R Trankle¹, Justin M Canada¹, Dinesh Kadariya¹, Roshanak Markley¹, Horacio Medina De Chazal¹, Janet Pinson¹, Adam Fox¹, Benjamin W Van Tassell¹, Antonio Abbate¹, Daniel Grinnan¹.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2019 PMID： 30418047 PMCID： PMC6913087 DOI： 10.1164/rccm.201809-1631LE

Source DB: PubMed Journal: Am J Respir Crit Care Med ISSN： 1073-449X Impact factor: 21.405

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11 in total

1. Cardiopulmonary exercise testing in patients with pulmonary arterial hypertension: an evidence-based review.

Authors: Ross Arena; Carl J Lavie; Richard V Milani; Jonathan Myers; Marco Guazzi
Journal: J Heart Lung Transplant Date: 2009-12-06 Impact factor: 10.247

2. Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study.

Authors: Benjamin W Van Tassell; Nayef A Abouzaki; Claudia Oddi Erdle; Salvatore Carbone; Cory R Trankle; Ryan D Melchior; Jeremy S Turlington; Clinton J Thurber; Sanah Christopher; Dave L Dixon; Daniel T Fronk; Christopher S Thomas; Scott W Rose; Leo F Buckley; Charles A Dinarello; Giuseppe Biondi-Zoccai; Antonio Abbate
Journal: J Cardiovasc Pharmacol Date: 2016-06 Impact factor: 3.105

Review 3. Immune dysregulation and endothelial dysfunction in pulmonary arterial hypertension: a complex interplay.

Authors: Alice Huertas; Frédéric Perros; Ly Tu; Sylvia Cohen-Kaminsky; David Montani; Peter Dorfmüller; Christophe Guignabert; Marc Humbert
Journal: Circulation Date: 2014-03-25 Impact factor: 29.690

4. Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results From REDHART (Recently Decompensated Heart Failure Anakinra Response Trial).

Authors: Benjamin W Van Tassell; Justin Canada; Salvatore Carbone; Cory Trankle; Leo Buckley; Claudia Oddi Erdle; Nayef A Abouzaki; Dave Dixon; Dinesh Kadariya; Sanah Christopher; Aaron Schatz; Jessica Regan; Michele Viscusi; Marco Del Buono; Ryan Melchior; Pranav Mankad; Juan Lu; Robin Sculthorpe; Giuseppe Biondi-Zoccai; Edward Lesnefsky; Ross Arena; Antonio Abbate
Journal: Circ Heart Fail Date: 2017-11 Impact factor: 8.790

5. Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial.

Authors: Paul M Ridker; Jean G MacFadyen; Brendan M Everett; Peter Libby; Tom Thuren; Robert J Glynn
Journal: Lancet Date: 2017-11-13 Impact factor: 79.321

6. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.

Authors: Paul M Ridker; Brendan M Everett; Tom Thuren; Jean G MacFadyen; William H Chang; Christie Ballantyne; Francisco Fonseca; Jose Nicolau; Wolfgang Koenig; Stefan D Anker; John J P Kastelein; Jan H Cornel; Prem Pais; Daniel Pella; Jacques Genest; Renata Cifkova; Alberto Lorenzatti; Tamas Forster; Zhanna Kobalava; Luminita Vida-Simiti; Marcus Flather; Hiroaki Shimokawa; Hisao Ogawa; Mikael Dellborg; Paulo R F Rossi; Roland P T Troquay; Peter Libby; Robert J Glynn
Journal: N Engl J Med Date: 2017-08-27 Impact factor: 91.245

Review 7. Updated clinical classification of pulmonary hypertension.

Authors: Gerald Simonneau; Michael A Gatzoulis; Ian Adatia; David Celermajer; Chris Denton; Ardeschir Ghofrani; Miguel Angel Gomez Sanchez; R Krishna Kumar; Michael Landzberg; Roberto F Machado; Horst Olschewski; Ivan M Robbins; Rogiero Souza
Journal: J Am Coll Cardiol Date: 2013-12-24 Impact factor: 24.094

8. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension.

Authors: Elaine Soon; Alan M Holmes; Carmen M Treacy; Natalie J Doughty; Laura Southgate; Rajiv D Machado; Richard C Trembath; Simon Jennings; Lucy Barker; Paul Nicklin; Christoph Walker; David C Budd; Joanna Pepke-Zaba; Nicholas W Morrell
Journal: Circulation Date: 2010-08-16 Impact factor: 29.690

9. Predicting peak oxygen consumption during a conservative ramping protocol: implications for the heart failure population.

Authors: Ross Arena; Reed Humphrey; Mary Ann Peberdy; Michael Madigan
Journal: J Cardiopulm Rehabil Date: 2003 May-Jun Impact factor: 2.081

10. Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling.

Authors: Josephine Pickworth; Alexander Rothman; James Iremonger; Helen Casbolt; Kay Hopkinson; Peter M Hickey; Santhi Gladson; Sheila Shay; Nicholas W Morrell; Sheila E Francis; James D West; Allan Lawrie
Journal: Pulm Circ Date: 2017-09-22 Impact factor: 3.017

26 in total

1. Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension.

Authors: Jason M Elinoff; Adrien J Mazer; Rongman Cai; Mengyun Lu; Grace Graninger; Bonnie Harper; Gabriela A Ferreyra; Junfeng Sun; Michael A Solomon; Robert L Danner
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2019-10-16 Impact factor: 5.464

2. Cytokines, Chemokines, and Inflammation in Pulmonary Arterial Hypertension.

Authors: Shuxin Liang; Ankit A Desai; Stephen M Black; Haiyang Tang
Journal: Adv Exp Med Biol Date: 2021 Impact factor: 2.622

Review 3. Emerging therapies for right ventricular dysfunction and failure.

Authors: Anna Klinke; Torben Schubert; Marion Müller; Ekaterina Legchenko; Jason G E Zelt; Tsukasa Shimauchi; L Christian Napp; Alexander M K Rothman; Sébastien Bonnet; Duncan J Stewart; Georg Hansmann; Volker Rudolph
Journal: Cardiovasc Diagn Ther Date: 2020-10

4. Update in Pulmonary Vascular Diseases and Right Ventricular Dysfunction 2019.

Authors: Elena A Goncharova; Stephen Y Chan; Corey E Ventetuolo; Norbert Weissmann; Ralph T Schermuly; Christopher J Mullin; Mark T Gladwin
Journal: Am J Respir Crit Care Med Date: 2020-07-01 Impact factor: 21.405

Review 5. Endothelial Senescence: A New Age in Pulmonary Hypertension.

Authors: Miranda K Culley; Stephen Y Chan
Journal: Circ Res Date: 2022-03-17 Impact factor: 17.367

6. Pirfenidone ameliorates pulmonary arterial pressure and neointimal remodeling in experimental pulmonary arterial hypertension by suppressing NLRP3 inflammasome activation.

Authors: Emmanouil Mavrogiannis; Quint A J Hagdorn; Venetia Bazioti; Johannes M Douwes; Diederik E Van Der Feen; Silke U Oberdorf-Maass; Marit Westerterp; Rolf M F Berger
Journal: Pulm Circ Date: 2022-07-01 Impact factor: 2.886