Literature DB >> 30417788

Epidemics and Peptide Vaccine Response: A Brief Review.

Ashesh Nandy1, Sumanta Dey1, Proyasha Roy1, Subhash C Basak2.   

Abstract

We briefly review the situations arising out of epidemics that erupt rather suddenly, threatening life and livelihoods of humans. Ebola, Zika and the Nipah virus outbreaks are recent examples where the viral epidemics have led to considerably high degree of fatalities or debilitating consequences. The problems are accentuated by a lack of drugs or vaccines effective against the new and emergent viruses, and the inordinate amount of temporal and financial resources that are required to combat the novel pathogens. Progress in computational, biological and informational sciences have made it possible to consider design of synthetic vaccines that can be rapidly developed and deployed to help stem the damages. In this review, we consider the pros and cons of this new paradigm and suggest a new system where the manufacturing process can be decentralized to provide more targeted vaccines to meet the urgent needs of protection in case of a rampaging epidemic. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Keywords:  Ebola vaccine; Influenza virus; MHC; Nipah virus; Peptide vaccines; Publiczzm321990health; Surface exposed conserved segments.

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Year:  2018        PMID: 30417788     DOI: 10.2174/1568026618666181112144745

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  4 in total

1.  Combatting future variants of SARS-CoV-2 using an in-silico peptide vaccine approach by targeting the spike protein.

Authors:  Subhamoy Biswas; Sumanta Dey; Shreyans Chatterjee; Ashesh Nandy
Journal:  Med Hypotheses       Date:  2022-02-22       Impact factor: 1.538

2.  Smart therapies against global pandemics: A potential of short peptides.

Authors:  Vasso Apostolopoulos; Joanna Bojarska; Jack Feehan; John Matsoukas; Wojciech Wolf
Journal:  Front Pharmacol       Date:  2022-08-15       Impact factor: 5.988

3.  Antigenic and conserved peptides from diverse Helicobacter pylori antigens.

Authors:  Cecília R C Calado
Journal:  Biotechnol Lett       Date:  2022-03-11       Impact factor: 2.716

4.  New Computational Approach for Peptide Vaccine Design Against SARS-COV-2.

Authors:  Subhamoy Biswas; Smarajit Manna; Ashesh Nandy; Subhash C Basak
Journal:  Int J Pept Res Ther       Date:  2021-07-10       Impact factor: 1.931

  4 in total

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