Literature DB >> 30417292

Effect of 30-Day Hindlimb Unloading and Hypergravity on Bone Marrow Stromal Progenitors in C57Bl/6N Mice.

E A Markina1, I V Andrianova2, A S Shtemberg2, L B Buravkova2.   

Abstract

We studied the effect of 30-day hindlimb unloading and subsequent simulated hypergravity on the cellularity and proliferative, clonogenic, and differentiation potential of bone marrow stromal progenitors in mice. Clonogenic and differentiation activity of stromal cells decreased after unloading; proliferative and differentiation activity of bone marrow stromal progenitors increased after hypergravity simulation. Our findings demonstrated negative effect of unloading on functional activity of mouse bone marrow stromal progenitors. Short-term hypergravity after unloading produced a stimulating effect on the bone marrow stromal progenitors.

Entities:  

Keywords:  bone marrow; hindlimb unloading; hypergravity; stromal progenitors

Mesh：

Year:  2018        PMID： 30417292     DOI： 10.1007/s10517-018-4301-9

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  4 in total

1.  Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice.

Authors:  Zebing Hu; Lijun Zhang; Han Wang; Yixuan Wang; Yingjun Tan; Lei Dang; Ke Wang; Zhongyang Sun; Gaozhi Li; Xinsheng Cao; Shu Zhang; Fei Shi; Ge Zhang
Journal:  Stem Cell Res Ther       Date:  2020-02-13       Impact factor: 6.832

2.  Effect of simulated microgravity conditions of hindlimb unloading on mice hematopoietic and mesenchymal stromal cells.

Authors:  Shiyun Dai; Fanxuan Kong; Chao Liu; Fengjun Xiao; Xiwen Dong; Yikun Zhang; Hua Wang
Journal:  Cell Biol Int       Date:  2020-08-08       Impact factor: 3.612

3.  Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.

Authors:  Linda Rubinstein; Amber M Paul; Charles Houseman; Metadel Abegaz; Steffy Tabares Ruiz; Nathan O'Neil; Gilad Kunis; Racheli Ofir; Jacob Cohen; April E Ronca; Ruth K Globus; Candice G T Tahimic
Journal:  Cells       Date:  2021-04-19       Impact factor: 6.600

4.  Artificially altered gravity elicits cell homeostasis imbalance in planarian worms, and cerium oxide nanoparticles counteract this effect.

Authors:  Alessandra Salvetti; Andrea Degl'Innocenti; Gaetana Gambino; Jack J W A van Loon; Chiara Ippolito; Sandra Ghelardoni; Eric Ghigo; Luca Leoncino; Mirko Prato; Leonardo Rossi; Gianni Ciofani
Journal:  J Biomed Mater Res A       Date:  2021-05-07       Impact factor: 4.396
  4 in total

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