Literature DB >> 30416521

Corrigendum to "Pregabalin Effect on Acute and Chronic Pain after Cardiac Surgery".

Aik Bouzia1, Vassilios Tassoudis2, Menelaos Karanikolas3, George Vretzakis2, Argyro Petsiti2, Nikolaos Tsilimingas4, Elena Arnaoutoglou2.   

Abstract

[This corrects the article DOI: 10.1155/2017/2753962.].

Entities:  

Year:  2018        PMID: 30416521      PMCID: PMC6207855          DOI: 10.1155/2018/5981895

Source DB:  PubMed          Journal:  Anesthesiol Res Pract        ISSN: 1687-6962


In the article titled “Pregabalin Effect on Acute and Chronic Pain after Cardiac Surgery” [1], the presentation of the results as originally published in Table 2 can be a source of confusion for the careful reader who tries to understand these numbers, as was raised in Theodorou and Bali [2]. In order to make the presentation of these numbers more accurate, it is important to clarify that the amounts of morphine listed in the line “Morphine use in first 24 hours” do not include the amount of morphine given in the first 8 hours. Therefore, the description of the line in question should be corrected from “Morphine use in first 24 hours” to the more accurate “Morphine use in postoperative hours 9–24.” The corrected table is shown below.
Table 2

Postoperative analgesic use and pain intensity. Data reported as median (minimum, maximum). Values for comparisons between study groups were calculated using the Kruskal–Wallis or chi-square tests as appropriate. Values for significance were adjusted to 0.05/12 = 0.0042 using Bonferroni correction for multiple comparisons.

VariableGroup 1 (control) N=31 Group 2 (pregabalin 75 mg) N=31Group 3 (pregabalin 150 mg) N=31
Intraoperative fentanyl (mcg)200 (150, 350)200 (100, 350)200 (50, 300)0.689
Intraoperative remifentanil (mcg)420 (380, 600)420 (360, 480)400 (360, 500)0.168
Boluses requested12 (4, 74)6 (0, 27)4 (1, 26)0.000
Boluses given10 (4, 28)6 (0, 14)4 (1, 13)0.000
VRS at 8 hours4 (2, 6)3 (3, 4)3 (0, 6)0.001
VRS at 24 hours1 (0, 5)1 (0, 4)0 (0, 3)0.007
VRS at 3 months3 (2, 5)2 (1, 3)2 (1, 3)0.000
Morphine use in first 8 hours (mg)14 (12, 17)13 (11, 16)12 (11, 14)0.000
Morphine use in postoperative hours 9–24 (mg)19.5 (16, 30)16 (14, 22)15 (12.5, 18)0.000
Vomiting at 24 hours6430.535
Use of analgesics at 3 months2616100.000
Sleep disturbance at 3 months16530.000
  2 in total

1.  Pregabalin Effect on Acute and Chronic Pain after Cardiac Surgery.

Authors:  Aik Bouzia; Vassilios Tassoudis; Menelaos Karanikolas; George Vretzakis; Argyro Petsiti; Nikolaos Tsilimingas; Elena Arnaoutoglou
Journal:  Anesthesiol Res Pract       Date:  2017-04-30

2.  Comment on "Pregabalin Effect on Acute and Chronic Pain after Cardiac Surgery".

Authors:  Elena Theodorou; Evagelia Bali
Journal:  Anesthesiol Res Pract       Date:  2018-06-05
  2 in total

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