| Literature DB >> 30416521 |
Aik Bouzia1, Vassilios Tassoudis2, Menelaos Karanikolas3, George Vretzakis2, Argyro Petsiti2, Nikolaos Tsilimingas4, Elena Arnaoutoglou2.
Abstract
[This corrects the article DOI: 10.1155/2017/2753962.].Entities:
Year: 2018 PMID: 30416521 PMCID: PMC6207855 DOI: 10.1155/2018/5981895
Source DB: PubMed Journal: Anesthesiol Res Pract ISSN: 1687-6962
Postoperative analgesic use and pain intensity. Data reported as median (minimum, maximum). Values for comparisons between study groups were calculated using the Kruskal–Wallis or chi-square tests as appropriate. Values for significance were adjusted to 0.05/12 = 0.0042 using Bonferroni correction for multiple comparisons.
| Variable | Group 1 (control) | Group 2 (pregabalin 75 mg) | Group 3 (pregabalin 150 mg) | |
|---|---|---|---|---|
| Intraoperative fentanyl (mcg) | 200 (150, 350) | 200 (100, 350) | 200 (50, 300) | 0.689 |
| Intraoperative remifentanil (mcg) | 420 (380, 600) | 420 (360, 480) | 400 (360, 500) | 0.168 |
| Boluses requested | 12 (4, 74) | 6 (0, 27) | 4 (1, 26) | 0.000 |
| Boluses given | 10 (4, 28) | 6 (0, 14) | 4 (1, 13) | 0.000 |
| VRS at 8 hours | 4 (2, 6) | 3 (3, 4) | 3 (0, 6) | 0.001 |
| VRS at 24 hours | 1 (0, 5) | 1 (0, 4) | 0 (0, 3) | 0.007 |
| VRS at 3 months | 3 (2, 5) | 2 (1, 3) | 2 (1, 3) | 0.000 |
| Morphine use in first 8 hours (mg) | 14 (12, 17) | 13 (11, 16) | 12 (11, 14) | 0.000 |
| Morphine use in postoperative hours 9–24 (mg) | 19.5 (16, 30) | 16 (14, 22) | 15 (12.5, 18) | 0.000 |
| Vomiting at 24 hours | 6 | 4 | 3 | 0.535 |
| Use of analgesics at 3 months | 26 | 16 | 10 | 0.000 |
| Sleep disturbance at 3 months | 16 | 5 | 3 | 0.000 |