Literature DB >> 30416081

Mechanisms of HLA-DP Antigen Processing and Presentation Revisited.

Mark Anczurowski1, Naoto Hirano2.   

Abstract

Polymorphisms in HLA-DP can modulate interactions with the invariant chain chaperone, contributing independently to differences in the peptide repertoire presented on DP. The resulting presentation of intracellular antigens directly to CD4+ T cells may partly explain genetic and clinical studies describing previously unexplained links between polymorphism in DP and disease.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  HLA Class II; HLA-DP; autoimmune disease; cancer; invariant chain; viral disease

Mesh：

Substances：

Year:  2018        PMID： 30416081     DOI： 10.1016/j.it.2018.10.008

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  9 in total

1.  Variation and expression of HLA-DPB1 gene in HBV infection.

Authors:  Guojin Ou; Xiao Liu; Haixia Xu; Xin Ji; Xiaojuan Liu; Jue Wang
Journal:  Immunogenetics       Date:  2021-03-12       Impact factor: 2.846

2.  Exploration of the pathogenesis of Sjögren's syndrome via DNA methylation and transcriptome analyses.

Authors:  Yu Du; Jie Li; Jianhong Wu; Fanxin Zeng; Chengsong He
Journal:  Clin Rheumatol       Date:  2022-05-13       Impact factor: 3.650

Review 3.  HLA associations in inflammatory arthritis: emerging mechanisms and clinical implications.

Authors:  Robert Busch; Simon Kollnberger; Elizabeth D Mellins
Journal:  Nat Rev Rheumatol       Date:  2019-06       Impact factor: 20.543

4.  HLA-DPB1 alleles in hepatitis B vaccine response: A meta-analysis.

Authors:  Guojin Ou; Xiaojuan Liu; Yongmei Jiang
Journal:  Medicine (Baltimore)       Date:  2021-04-09       Impact factor: 1.817

5.  MHC-II constrains the natural neutralizing antibody response to the SARS-CoV-2 spike RBM in humans.

Authors:  Andrea Castro; Kivilcim Ozturk; Maurizio Zanetti; Hannah Carter
Journal:  bioRxiv       Date:  2020-12-28

6.  Fine Mapping of the MHC Region Identifies Novel Variants Associated with HBV-Related Hepatocellular Carcinoma in Han Chinese.

Authors:  Haoming Mai; Jiaxuan Chen; Haitao Chen; Zhiwei Liu; Guanlin Huang; Jialin Wang; Qianyi Xiao; Weihua Ren; Bin Zhou; Jinlin Hou; Deke Jiang
Journal:  J Hepatocell Carcinoma       Date:  2021-08-16

7.  Isolated Pre-existing HLA-DP Donor-Specific Antibodies are Associated With Poorer Outcomes in Renal Transplantation.

Authors:  Adrienne Seitz; Katherine Mounsey; Pamela Hughes; Katherine Cullen; Matthew Welberry Smith; Sunil Daga; Clive Carter; Brendan Clark; Richard Baker
Journal:  Kidney Int Rep       Date:  2022-08-03

8.  Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations.

Authors:  Máté Manczinger; Gábor Boross; Lajos Kemény; Viktor Müller; Tobias L Lenz; Balázs Papp; Csaba Pál
Journal:  PLoS Biol       Date:  2019-01-31       Impact factor: 8.029

9.  The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers.

Authors:  Maryse Cloutier; Jean-Simon Fortin; Jacques Thibodeau
Journal:  BMC Immunol       Date:  2021-08-12       Impact factor: 3.615
  9 in total

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