Stéphane Northon1, Karine Boivin2, Louis Laurencelle3, Nicola Hagemeister4, Jacques A de Guise4. 1. Département des sciences de l'activité physique de l'Université du Québec à Trois-Rivières, 3351, boul. des Forges, Trois-Rivières, Québec G9A 5H7, Canada; Groupe de recherche sur les affections neuro-musculo-squelettiques, 3351, boul. des Forges, Trois-Rivières, Québec G9A 5H7, Canada. 2. Département des sciences de l'activité physique de l'Université du Québec à Trois-Rivières, 3351, boul. des Forges, Trois-Rivières, Québec G9A 5H7, Canada; Groupe de recherche sur les affections neuro-musculo-squelettiques, 3351, boul. des Forges, Trois-Rivières, Québec G9A 5H7, Canada. Electronic address: karine.boivin@uqtr.ca. 3. Département des sciences de l'activité physique de l'Université du Québec à Trois-Rivières, 3351, boul. des Forges, Trois-Rivières, Québec G9A 5H7, Canada. 4. Laboratoire en imagerie et orthopédie, Centre de recherche du Centre hospitalier de l'Université de Montréal, 900, rue Saint-Denis, Pavillon R, Montréal, Québec H2X 0A9, Canada; École de technologie supérieure, Département de génie de la production automatisée, 1100, rue Notre-Dame Ouest, Montréal, Québec H3C 1K3, Canada.
Abstract
BACKGROUND: Knee osteoarthritis alters joint stability but its kinematics during functional weight-bearing tasks remain unclear. We propose and validate an assessment technique for the quantification of knee alignment and stability in patients during a short single leg stance task. METHODS: Three-dimensional knee kinematics were acquired non-invasively from 31 knee osteoarthritis patients (subdivided as moderate or severe) and 15 asymptomatic individuals during six short single-leg stance tasks. Data of participants achieving ≥3 trials were retained. From flexion-extension signals, a data treatment method compared the average between-trial root-mean-square error (RMSE) across trial triplets, and the average within-trial range of movement (RoM) for two data windows. From secondary knee motions (ab/adduction and int/external rotations, anteroposterior and mediolateral translations), we extracted measures characterizing alignments (mean), largest deviations (maximum, minimum), and extent of micro-adjustments (RoM, length of knee excursion). Their sensitivity to disease and severity was determined using an ANOVA, and between-trial repeatability using ICC2,3. RESULTS: Ninety-four percent of patients achieved ≥3 trials. The retained trial triplet and window reduced the RMSE (2.15 to 1.54) and RoM (4.9° to 1.77°) for flexion-extension. Mean, minimum, and maximum measures were sensitive to disease for anteroposterior translations, and to severity for ab/adduction (P < 0.05). High repeatability was found for those measures (ICC ≥0.84). RoM and length of knee excursion, although sensitive to disease for anteroposterior translations, had lower ICC. CONCLUSION: The proposed technique is feasible and exposed measures of knee alignment sensitive to knee osteoarthritis, for instance, an anterior femoral shift and an increased adduction malalignment with greater severity.
BACKGROUND:Knee osteoarthritis alters joint stability but its kinematics during functional weight-bearing tasks remain unclear. We propose and validate an assessment technique for the quantification of knee alignment and stability in patients during a short single leg stance task. METHODS: Three-dimensional knee kinematics were acquired non-invasively from 31 knee osteoarthritispatients (subdivided as moderate or severe) and 15 asymptomatic individuals during six short single-leg stance tasks. Data of participants achieving ≥3 trials were retained. From flexion-extension signals, a data treatment method compared the average between-trial root-mean-square error (RMSE) across trial triplets, and the average within-trial range of movement (RoM) for two data windows. From secondary knee motions (ab/adduction and int/external rotations, anteroposterior and mediolateral translations), we extracted measures characterizing alignments (mean), largest deviations (maximum, minimum), and extent of micro-adjustments (RoM, length of knee excursion). Their sensitivity to disease and severity was determined using an ANOVA, and between-trial repeatability using ICC2,3. RESULTS: Ninety-four percent of patients achieved ≥3 trials. The retained trial triplet and window reduced the RMSE (2.15 to 1.54) and RoM (4.9° to 1.77°) for flexion-extension. Mean, minimum, and maximum measures were sensitive to disease for anteroposterior translations, and to severity for ab/adduction (P < 0.05). High repeatability was found for those measures (ICC ≥0.84). RoM and length of knee excursion, although sensitive to disease for anteroposterior translations, had lower ICC. CONCLUSION: The proposed technique is feasible and exposed measures of knee alignment sensitive to knee osteoarthritis, for instance, an anterior femoral shift and an increased adduction malalignment with greater severity.
Authors: R van der Straaten; M Wesseling; I Jonkers; B Vanwanseele; A K B D Bruijnes; J Malcorps; J Bellemans; J Truijen; L De Baets; A Timmermans Journal: PLoS One Date: 2020-05-14 Impact factor: 3.240