Literature DB >> 30415106

Palliative treatment of germ cell cancer.

Christoph Oing1, Patrizia Giannatempo2, Friedemann Honecker3, Karin Oechsle1, Carsten Bokemeyer1, Jörg Beyer4.   

Abstract

Most patients with metastatic germ-cell cancer (GCC) can be cured by cisplatin-based combination chemotherapy. Yet, about 10-15% of metastatic GCC patients will eventually die of their disease. This narrative review focuses on treatment options when cure is no longer realistic.
Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Drug therapy; Germ cell cancer; Germ cell tumor; Palliative treatment; Platinum-refractory

Mesh：

Substances：

Year:  2018        PMID： 30415106     DOI： 10.1016/j.ctrv.2018.10.007

Source DB:  PubMed          Journal:  Cancer Treat Rev        ISSN： 0305-7372            Impact factor:   12.111


  10 in total

Review 1.  [Testicular tumours from a clinical point of view : What urologists and oncologists need to know from the pathologist about testicular cancer].

Authors:  Christoph Oing; Christian Daniel Fankhauser
Journal:  Pathologie (Heidelb)       Date:  2022-09-26

2.  Treatment of refractory germ-cell tumours with single-agent cabazitaxel: a German Testicular Cancer Study Group case series.

Authors:  Christoph Oing; Marcus Hentrich; Anja Lorch; Dietrich Gläser; Holger Rumpold; Sebastian Ochsenreither; Stephan Richter; Annette Dieing; Stefanie Zschäbitz; Ronnie Rodrigues Pereira; Carsten Bokemeyer; Christoph Seidel
Journal:  J Cancer Res Clin Oncol       Date:  2019-12-14       Impact factor: 4.553

3.  Efficacy of Quercetin-Sensitized Cisplatin against N-Nitroso-NMethylurea Induced Testicular Carcinogenesis in Wistar Rats.

Authors:  Hend Hgm El-Diasty; Hassan El-Sayyad; Sherif Refaat; Heba A El-Ghaweet
Journal:  Asian Pac J Cancer Prev       Date:  2021-01-01

4.  ARID1A Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while ARID1A Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition.

Authors:  Lukas Kurz; Alissa Miklyaeva; Margaretha A Skowron; Nina Overbeck; Gereon Poschmann; Teresa Becker; Katharina Eul; Thomas Kurz; Stefan Schönberger; Gabriele Calaminus; Kai Stühler; Emily Dykhuizen; Peter Albers; Daniel Nettersheim
Journal:  Cancers (Basel)       Date:  2020-04-07       Impact factor: 6.639

5.  Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights.

Authors:  Melanie R Müller; Aaron Burmeister; Margaretha A Skowron; Alexa Stephan; Felix Bremmer; Gamal A Wakileh; Patrick Petzsch; Karl Köhrer; Peter Albers; Daniel Nettersheim
Journal:  Clin Epigenetics       Date:  2022-01-07       Impact factor: 6.551

6.  Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors.

Authors:  Kai Funke; Robert Düster; Prince De-Graft Wilson; Lena Arévalo; Matthias Geyer; Hubert Schorle
Journal:  Cancers (Basel)       Date:  2022-03-26       Impact factor: 6.639

7.  Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level.

Authors:  Margaretha A Skowron; Katharina Eul; Alexa Stephan; Gillian F Ludwig; Gamal A Wakileh; Arthur Bister; Christian Söhngen; Katharina Raba; Patrick Petzsch; Gereon Poschmann; Edmund Osei Kuffour; Daniel Degrandi; Shafaqat Ali; Constanze Wiek; Helmut Hanenberg; Carsten Münk; Kai Stühler; Karl Köhrer; Elvira Mass; Daniel Nettersheim
Journal:  Mol Oncol       Date:  2022-07-26       Impact factor: 7.449

8.  CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms.

Authors:  Margaretha A Skowron; Marieke Vermeulen; Anna Winkelhausen; Teresa K Becker; Felix Bremmer; Patrick Petzsch; Stefan Schönberger; Gabriele Calaminus; Karl Köhrer; Peter Albers; Daniel Nettersheim
Journal:  Br J Cancer       Date:  2020-05-18       Impact factor: 7.640

9.  The impact of a supranetwork multidisciplinary team (SMDT) on decision-making in testicular cancers: a 10-year overview of the Anglian Germ Cell Cancer Collaborative Group (AGCCCG).

Authors:  Daniel Berney; Anju Sahdev; Jonathan Shamash; Wendy Ansell; Constantine Alifrangis; Benjamin Thomas; Peter Wilson; Sara Stoneham; Danish Mazhar; Anne Warren; Tristan Barrett; Susanna Alexander; Sarah Rudman; Michelle Lockley
Journal:  Br J Cancer       Date:  2020-09-29       Impact factor: 7.640

10.  The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas.

Authors:  Margaretha A Skowron; Teresa K Becker; Lukas Kurz; Sina Jostes; Felix Bremmer; Florian Fronhoffs; Kai Funke; Gamal A Wakileh; Melanie R Müller; Aaron Burmeister; Thomas Lenz; Anja Stefanski; Kai Stühler; Patrick Petzsch; Karl Köhrer; Peter Altevogt; Peter Albers; Glen Kristiansen; Hubert Schorle; Daniel Nettersheim
Journal:  Mol Oncol       Date:  2021-08-02       Impact factor: 6.603
  10 in total

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