Cynthia Aristei1, Valentina Lancellotta2, Marco Piergentini3, Giacomo Costantini3, Simonetta Saldi4, Sara Chierchini5, Antonella Cavalli4, Luca Di Renzo3, Oscar Fiorucci6, Massimo Guasticchi6, Vittorio Bini7, Alessandro Ricci3. 1. Radiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia and Perugia General Hospital, Italy. Electronic address: cynthia.aristei@unipg.it. 2. Radiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia and Perugia General Hospital, Italy. 3. 3dific srl, Innovative Startup, University of Perugia, Italy. 4. Radiation Oncology Section, Department of Haematology, Medical and Radiation Oncology and Gastroenterology, Perugia General Hospital, Italy. 5. Radiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia, Italy. 6. Degree Course (BSc) for Radiography Technicians, Department of Surgical and Biomedical Science, University of Perugia and Perugia General Hospital, Italy. 7. Internal Medicine, Endocrine and Metabolic Science Section, Department of Medicine, University of Perugia, Italy.
Abstract
PURPOSE: High-dose-rate, multicatheter interstitial brachytherapy is technically complex and operator-dependent, requiring lengthy training and specialized skills. Furthermore, until the advent of contouring on computerized tomography (CT) images, difficulties existed in locating the target volume precisely. The present article reports the results of a study that aimed at producing and validating a 3D-printed template to aid in target volume localization for multicatheter interstitial brachytherapy in patients with breast cancer. METHODS AND MATERIALS: Thirteen patients, candidates for accelerated partial breast irradiation or boost, were enrolled in the study. The target volume was defined on CT slices, and a template with empty spaces corresponding to the target volume projection on the patient's skin was produced by a 3D printer. The procedure was compared with the standard method followed in our center (1) visually, by assessing overlap between the target volume projections on the patient's skin, (2) by X-ray findings, and (3) by intraclass correlation coefficient. RESULTS: Visual assessment and X-ray findings showed the 3D-printed target volume always fell within the standard volume in all 13 patients. The intraclass correlation coefficient indicated moderate agreement for both the medial and the lateral skin projections. CONCLUSIONS: The 3-D printed templates constitute a quick, easy, and reliable method to localize the target volume for high-dose-rate interstitial multicathether brachytherapy in patients with breast cancer and can safely be used in clinical practice.
PURPOSE: High-dose-rate, multicatheter interstitial brachytherapy is technically complex and operator-dependent, requiring lengthy training and specialized skills. Furthermore, until the advent of contouring on computerized tomography (CT) images, difficulties existed in locating the target volume precisely. The present article reports the results of a study that aimed at producing and validating a 3D-printed template to aid in target volume localization for multicatheter interstitial brachytherapy in patients with breast cancer. METHODS AND MATERIALS: Thirteen patients, candidates for accelerated partial breast irradiation or boost, were enrolled in the study. The target volume was defined on CT slices, and a template with empty spaces corresponding to the target volume projection on the patient's skin was produced by a 3D printer. The procedure was compared with the standard method followed in our center (1) visually, by assessing overlap between the target volume projections on the patient's skin, (2) by X-ray findings, and (3) by intraclass correlation coefficient. RESULTS: Visual assessment and X-ray findings showed the 3D-printed target volume always fell within the standard volume in all 13 patients. The intraclass correlation coefficient indicated moderate agreement for both the medial and the lateral skin projections. CONCLUSIONS: The 3-D printed templates constitute a quick, easy, and reliable method to localize the target volume for high-dose-rate interstitial multicathether brachytherapy in patients with breast cancer and can safely be used in clinical practice.
Keywords:
3D printing; Breast cancer; Breast template; High-dose-rate interstitial multicathether brachytherapy; Target volume localization; Three dimensional
Authors: Michael K Rooney; David M Rosenberg; Steve Braunstein; Adam Cunha; Antonio L Damato; Eric Ehler; Todd Pawlicki; James Robar; Ken Tatebe; Daniel W Golden Journal: J Appl Clin Med Phys Date: 2020-05-27 Impact factor: 2.102
Authors: Gabriel P Fonseca; Jacob G Johansen; Ryan L Smith; Luc Beaulieu; Sam Beddar; Gustavo Kertzscher; Frank Verhaegen; Kari Tanderup Journal: Phys Imaging Radiat Oncol Date: 2020-09-28