Expression of Concern to IRE1a constitutes a negative feedback loop with BMP2 and acts as a novel mediator in modulating osteogenic differentiation.

The Editors-in-Chief are issuing an editorial expression of concern to alert readers that after publication of this article1 concerns have been raised with respect to the integrity of Figs 1c, 1e, 2b, 6b, and 7a. Chongqing Medical University is investigating these concerns and appropriate editorial action will be taken once the outcome of this investigation is known. The authors do not agree with this notice.

Addendum to: Cell Death and Disease (2014)5:e1239 10.1038/cddis.2014.194 published online 22 May 2014

The Editors-in-Chief are issuing an editorial expression of concern to alert readers that after publication of this article[1] concerns have been raised with respect to the integrity of Figs. 1c, e, 2b, 6b, and 7a. Chongqing Medical University is investigating these concerns and appropriate editorial action will be taken once the outcome of this investigation is known. The authors do not agree with this notice.