Literature DB >> 30412206

Wnt is back in drugmakers' sights, but is it druggable?

Cormac Sheridan.   

Abstract

Mesh：

Year:  2018        PMID： 30412206     DOI： 10.1038/nbt1118-1028

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  3 in total

Review 1.  Three decades of Wnts: a personal perspective on how a scientific field developed.

Authors:  Roel Nusse; Harold Varmus
Journal:  EMBO J       Date:  2012-05-22       Impact factor: 11.598

Review 2.  Wnt signalling: conquering complexity.

Authors:  Katrin E Wiese; Roel Nusse; Renée van Amerongen
Journal:  Development       Date:  2018-06-26       Impact factor: 6.868

3.  Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity.

Authors:  Stefani Spranger; Riyue Bao; Thomas F Gajewski
Journal:  Nature       Date:  2015-05-11       Impact factor: 49.962
  3 in total
  5 in total

1.  Evaluation of the CRISPR/Cas9 directed mutant TP53 gene repairing effect in human prostate cancer cell line PC-3.

Authors:  Muhammet Burak Batır; Ergin Şahin; Fethi Sırrı Çam
Journal:  Mol Biol Rep       Date:  2019-11-07       Impact factor: 2.316

2.  Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9.

Authors:  Li-Shu Zhang; Xunlei Kang; Jianming Lu; Yuannyu Zhang; Xiaofeng Wu; Guojin Wu; Junke Zheng; Rubina Tuladhar; Heping Shi; Qiaoling Wang; Lorraine Morlock; Huiyu Yao; Lily Jun-Shen Huang; Pascal Maire; James Kim; Noelle Williams; Jian Xu; Chuo Chen; Cheng Cheng Zhang; Lawrence Lum
Journal:  EBioMedicine       Date:  2018-12-06       Impact factor: 8.143

Review 3.  Small Molecule Wnt Pathway Modulators from Natural Sources: History, State of the Art and Perspectives.

Authors:  Artem Blagodatski; Antonina Klimenko; Lee Jia; Vladimir L Katanaev
Journal:  Cells       Date:  2020-03-02       Impact factor: 6.600

4.  Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.

Authors:  Elliott D Bayle; Fredrik Svensson; Benjamin N Atkinson; David Steadman; Nicky J Willis; Hannah L Woodward; Paul Whiting; Jean-Paul Vincent; Paul V Fish
Journal:  J Med Chem       Date:  2021-03-30       Impact factor: 7.446

5.  The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.

Authors:  Margherita Pergolizzi; Laura Bizzozero; Federico Bussolino; Marco Arese; Federica Maione; Elena Maldi; Claudio Isella; Marco Macagno; Elisa Mariella; Alberto Bardelli; Enzo Medico; Caterina Marchiò; Guido Serini; Federica Di Nicolantonio
Journal:  J Exp Clin Cancer Res       Date:  2022-09-02
  5 in total

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