Literature DB >> 304116

[Aqueous humor levels of gentamicin after parenteral, subconjunctival and topical administration (aithor's transl)].

D Utermann, K Matz, K Meyer.   

Abstract

The purpose of this study was to determine the concentration of Gentamicin in blood serum and primary aqueous humor at varying periods of time after intravenous, intramuscular, subconjunctival and topical administration of Gentamicin. Therapeutic effective levels in primary aqueous humor were measured only after subconjunctival injections. The only broad spectrum antibiotics are the aminoglykosides Gentamicin, Tobramycin, Sisomicin and Amikacin. For prompt treatment of bacterial endophthalmitis without bacterial culture and antibiotic sensitivity testing therefore subconjunctival injection of Gentamicin is necessary.

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Year:  1977        PMID: 304116

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  2 in total

1.  Ciprofloxacin concentration in the rabbit aqueous humor and vitreous following intravenous and subconjunctival administration.

Authors:  W Behrens-Baumann; J Martell
Journal:  Infection       Date:  1988       Impact factor: 3.553

2.  Azlocillin concentrations in human aqueous humor after intravenous and subconjunctival administration.

Authors:  W Behrens-Baumann; R Ansorg
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1983       Impact factor: 3.117

  2 in total

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