OBJECTIVE: To describe the currently accepted standard-of-care practice for surgical and medical management of newly diagnosed high-grade glioma. DATA SOURCES: Peer-reviewed journals, nationally accepted guidelines, and personal experience of the authors. CONCLUSION: There is a widely accepted standard-of-care treatment protocol for patients with newly diagnosed high-grade glioma that includes maximal safe resection followed by radiation therapy with concurrent and adjuvant temozolomide. The regimen is well-tolerated and side effects are manageable. IMPLICATIONS FOR NURSING PRACTICE: Nurses who are involved in the care of patients with newly diagnosed high-grade glioma should be familiar with the regimen and its side effects to provide crucial patient and caregiver education in an accurate and beneficial manner.
OBJECTIVE: To describe the currently accepted standard-of-care practice for surgical and medical management of newly diagnosed high-grade glioma. DATA SOURCES: Peer-reviewed journals, nationally accepted guidelines, and personal experience of the authors. CONCLUSION: There is a widely accepted standard-of-care treatment protocol for patients with newly diagnosed high-grade glioma that includes maximal safe resection followed by radiation therapy with concurrent and adjuvant temozolomide. The regimen is well-tolerated and side effects are manageable. IMPLICATIONS FOR NURSING PRACTICE: Nurses who are involved in the care of patients with newly diagnosed high-grade glioma should be familiar with the regimen and its side effects to provide crucial patient and caregiver education in an accurate and beneficial manner.
Authors: Tavarekere N Nagaraja; Ana C deCarvalho; Stephen L Brown; Brent Griffith; Katelynn Farmer; Susan Irtenkauf; Laura Hasselbach; Abir Mukherjee; Seamus Bartlett; O Grahm Valadie; Glauber Cabral; Robert A Knight; Ian Y Lee; George W Divine; James R Ewing Journal: Cancer Treat Res Commun Date: 2021-01-19