Literature DB >> 3040898

Immunization of monkeys with varicella-zoster virus glycoprotein antigens and their response to challenge with simian varicella virus.

K F Soike, P M Keller, R W Ellis.   

Abstract

African green monkeys (Cercopithecus aethiops) were immunized with three intramuscular injections of gpI, gpII, or gpIII glycoprotein antigens of varicella-zoster virus (VZV). Antibody responses to VZV were determined by enzyme-linked immunosorbent assay (ELISA) and to simian varicella virus (SVV) by immunofluorescence and by serum neutralization assays. Two weeks following the third immunization with VZV glycoproteins, the monkeys were challenged by inoculation of SVV. Antibodies to gpII or gpIII partially prevented infection by SVV, while the presence of antibodies to gpI was ineffective in preventing disease induced by SVV challenge. Factors affecting the immunogenicity of these antigens in this model are discussed.

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Year:  1987        PMID： 3040898     DOI： 10.1002/jmv.1890220403

Source DB:  PubMed          Journal:  J Med Virol        ISSN： 0146-6615            Impact factor:   2.327


  10 in total

Review 1.  Simian varicella in old world monkeys.

Authors:  Wayne L Gray
Journal:  Comp Med       Date:  2008-02       Impact factor: 0.982

2.  Identification of simian varicella virus homologues of varicella zoster virus genes.

Authors:  T M White; R Mahalingam; G Kolhatkar; D H Gilden
Journal:  Virus Genes       Date:  1997       Impact factor: 2.332

3.  A simian varicella virus (SVV) homolog to varicella-zoster virus gene 21 is expressed in monkey ganglia latently infected with SVV.

Authors:  P Clarke; W L Matlock; T Beer; D H Gilden
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

4.  Simian varicella virus pathogenesis.

Authors:  Ravi Mahalingam; Ilhem Messaoudi; Don Gilden
Journal:  Curr Top Microbiol Immunol       Date:  2010       Impact factor: 4.291

5.  Abortive intrabronchial infection of rhesus macaques with varicella-zoster virus provides partial protection against simian varicella virus challenge.

Authors:  Christine Meyer; Flora Engelmann; Nicole Arnold; David L Krah; Jan ter Meulen; Kristen Haberthur; Jesse Dewane; Ilhem Messaoudi
Journal:  J Virol       Date:  2014-11-19       Impact factor: 5.103

6.  Simian varicella virus DNA in dorsal root ganglia.

Authors:  R Mahalingam; D Smith; M Wellish; W Wolf; A N Dueland; R Cohrs; K Soike; D Gilden
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205

7.  Simian varicella virus induces apoptosis in monkey kidney cells by the intrinsic pathway and involves downregulation of bcl-2 expression.

Authors:  Subbiah Pugazhenthi; Donald H Gilden; Sreekala Nair; Anne McAdoo; Mary Wellish; Elizabeth Brazeau; Ravi Mahalingam
Journal:  J Virol       Date:  2009-07-15       Impact factor: 5.103

8.  Clinical and molecular aspects of varicella zoster virus infection.

Authors:  Don Gilden; Maria A Nagel; Ravi Mahalingam; Niklaus H Mueller; Elizabeth A Brazeau; Subbiah Pugazhenthi; Randall J Cohrs
Journal:  Future Neurol       Date:  2009-01-01

Review 9.  Animal models of varicella zoster virus infection.

Authors:  Kristen Haberthur; Ilhem Messaoudi
Journal:  Pathogens       Date:  2013-05-13

10.  Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans.

Authors:  Ilhem Messaoudi; Alexander Barron; Mary Wellish; Flora Engelmann; Alfred Legasse; Shannon Planer; Don Gilden; Janko Nikolich-Zugich; Ravi Mahalingam
Journal:  PLoS Pathog       Date:  2009-11-13       Impact factor: 6.823
  10 in total

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