Literature DB >> 30408435

Inflamed Astrocytes: A Path to Depression Led by Menin.

Fernanda Neutzling Kaufmann1, Caroline Menard2.   

Abstract

Increasing evidence supports a role for inflammation in the development of mood disorders. In this issue of Neuron, Leng et al. (2018) show that reduction of menin expression in astrocytes of stress-related brain regions exacerbates neuroinflammation, promoting the establishment of depression-like behaviors in mice.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30408435     DOI： 10.1016/j.neuron.2018.10.039

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  3 in total

1.  Folic Acid Attenuates Glial Activation in Neonatal Mice and Improves Adult Mood Disorders Through Epigenetic Regulation.

Authors:  Tiantian Zhao; Dong Wu; Jingyi Du; Guowei Liu; Guangyu Ji; Zixiao Wang; Fan Peng; Lajie Man; Wenjuan Zhou; Aijun Hao
Journal:  Front Pharmacol       Date:  2022-02-07       Impact factor: 5.810

2.  Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.

Authors:  Juan Ji; Shangze Li; Zikai Jiang; Jianbing Yu; Yuqin Sun; Zhenyu Cai; Yinfeng Dong; Xiulan Sun
Journal:  Int J Mol Sci       Date:  2022-09-16       Impact factor: 6.208

3.  Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacology.

Authors:  Xiansu Chi; Xiaoyan Xue; Jin Pan; Jiang Wu; Huishan Shi; Yong Wang; Yanting Lu; Zhe Zhang; Ke Ma
Journal:  Pharm Biol       Date:  2022-12       Impact factor: 3.889
  3 in total

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