| Literature DB >> 30407519 |
Fouad Madhi1,2, Corinne Levy2,3,4, Laurence Morin5, Philippe Minodier6, François Dubos7, Ferielle Zenkhri8, Marie Aliette Dommergues9, Ellia Mezgueldi10, Karine Levieux11, Stéphane Béchet2,3,4, Emmanuelle Varon12, Robert Cohen2,3,4,13.
Abstract
We describe here changes in the bacterial causes of pleural empyema before and after implementation of the 13-valent pneumococcal conjugate vaccine (PCV13) program in France (2009-2017). For 220 (39.3%) of 560 children, a bacterial cause was found. The frequency of pneumococcal infection decreased during the study from 79.1% in 2009 to 36.4% in 2017 (P < .001). Group A streptococcus is now the leading cause of documented empyema (45.5%).Entities:
Keywords: PCV13; bacterial pneumonia; children; empyema; pleural effusion
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Year: 2019 PMID: 30407519 DOI: 10.1093/jpids/piy103
Source DB: PubMed Journal: J Pediatric Infect Dis Soc ISSN: 2048-7193 Impact factor: 3.164