| Literature DB >> 3040472 |
R V Guntaka, S Gowda, H Wagner, D Simon.
Abstract
The effect of methylation of an enhancer on transcription was studied. A 245 bp enhancer-containing a fragment of the LTR of the avian sarcoma virus was methylated in vitro and ligated back into a vector which lacked the upstream enhancer sequence. The transient expression in QT6 cells indicated that methylation of the enhancer-containing sequence severely reduced the extent of transcription.Entities:
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Year: 1987 PMID： 3040472 DOI： 10.1016/0014-5793(87)80951-1
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124