Literature DB >> 3040445

Increase in IP3 precedes alpha-adrenoceptor-induced increase in force of contraction in cardiac muscle.

W Schmitz, H Scholz, J Scholz, M Steinfath.   

Abstract

In electrically driven left auricles isolated from rat hearts the alpha 1-adrenoceptor agonist phenylephrine increased inositol trisphosphate (IP3) and force of contraction. The increase in IP3 preceded the increase in force of contraction, indicating that the alpha 1-adrenoceptor-mediated increase in IP3 and force of contraction may have been causally related.

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Year:  1987        PMID： 3040445     DOI： 10.1016/0014-2999(87)90641-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  17 in total

Review 1.  On the mechanism of positive inotropic effects of alpha-adrenoceptor agonists.

Authors:  W Schmitz; C Kohl; J Neumann; H Scholz; J Scholz
Journal:  Basic Res Cardiol       Date:  1989       Impact factor: 17.165

2.  Effect of alpha 1-adrenoceptor stimulation with methoxamine and phenylephrine on spontaneously beating rabbit sino-atrial node cells.

Authors:  H Satoh; K Hashimoto
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-04       Impact factor: 3.000

3.  Effects of ischaemia, reperfusion and alpha 1-adrenergic receptor stimulation on the inositoltrisphosphate receptor population in rat heart atria and ventricles.

Authors:  B Huisamen; R Mouton; L H Opie; A Lochner
Journal:  Mol Cell Biochem       Date:  1994-11-09       Impact factor: 3.396

4.  Effects of carbachol and (-)-N6-phenylisopropyladenosine on myocardial inositol phosphate content and force of contraction.

Authors:  C Kohl; B Linck; W Schmitz; H Scholz; J Scholz; M Tóth
Journal:  Br J Pharmacol       Date:  1990-12       Impact factor: 8.739

5.  Effects of purinergic stimulation on the Ca current in single frog cardiac cells.

Authors:  J L Alvarez; K Mongo; F Scamps; G Vassort
Journal:  Pflugers Arch       Date:  1990-04       Impact factor: 3.657

Review 6.  Is there evidence of a role of the phosphoinositol-cycle in the myocardium?

Authors:  D de Chaffoy de Courcelles
Journal:  Mol Cell Biochem       Date:  1989 Jun 27-Jul 24       Impact factor: 3.396

7.  Norepinephrine-induced 1,2-diacylglycerol accumulation and change in its fatty acid composition in the isolated perfused rat heart.

Authors:  K Okumura; Y Shirai; J Kondo; H Hashimoto; T Ito; K Ogawa
Journal:  Mol Cell Biochem       Date:  1990-03-27       Impact factor: 3.396

8.  Alpha-adrenoceptor modulation of the efferent function of capsaicin-sensitive sensory neurones in guinea-pig isolated atria.

Authors:  S Amerini; A Rubino; L Mantelli; F Ledda
Journal:  Br J Pharmacol       Date:  1992-04       Impact factor: 8.739

Review 9.  Inositol phosphates in the heart: controversy and consensus.

Authors:  E A Woodcock
Journal:  J Mol Med (Berl)       Date:  1995-06       Impact factor: 4.599

10.  Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats.

Authors:  M Böhm; D Beuckelmann; F Diet; G Feiler; M J Lohse; E Erdmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-10       Impact factor: 3.000
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