Isaiah Tan1, Laurie Lomasney2, Gregory Scott Stacy3, Martin Lazarus4, Winnie Anne Mar1. 1. 1 Department of Radiology, University of Illinois College of Medicine, 1740 W Taylor St, Rm. 2483 (MC 931), Chicago, IL 60612. 2. 2 Loyola University Health System, Maywood, IL. 3. 3 University of Chicago Medical Center, Chicago, IL. 4. 4 NorthShore University Health System, Evanston, IL.
Abstract
OBJECTIVE: Voriconazole is an antifungal medication used primarily for the treatment of Candida and Aspergillus infections. A fairly newly described side effect of long-term voriconazole use is periostitis. The purpose of this article is to describe the main differential consideration-hypertrophic osteoarthropathy-and other differential diagnoses, including venous stasis, thyroid acropachy, and hypervitaminosis A. CONCLUSION: With knowledge of imaging appearance, clinical manifestations, and outcomes, radiologists can make an accurate diagnosis of voriconazole-induced periostitis, and clinical teams can initiate appropriate management.
OBJECTIVE:Voriconazole is an antifungal medication used primarily for the treatment of Candida and Aspergillus infections. A fairly newly described side effect of long-term voriconazole use is periostitis. The purpose of this article is to describe the main differential consideration-hypertrophic osteoarthropathy-and other differential diagnoses, including venous stasis, thyroid acropachy, and hypervitaminosis A. CONCLUSION: With knowledge of imaging appearance, clinical manifestations, and outcomes, radiologists can make an accurate diagnosis of voriconazole-induced periostitis, and clinical teams can initiate appropriate management.