| Literature DB >> 30402004 |
Xavier Buy1, Vittorio Catena1, Guilhem Roubaud2, Amandine Crombe1, Michèle Kind1, Jean Palussiere1.
Abstract
Occurrence of bone metastases is a common event in oncology. Bone metastases are associated with pain, functional impairment, and fractures, particularly when weight-bearing bones are involved. Management of bone metastases has been improved by the development of various interventional radiology consolidation techniques. Cementoplasty is based on injection of acrylic cement into a weakened bone to reinforce it and to control pain. This minimally invasive technique has proven its efficacy for flat bone submitted to compression forces. However, resistance to torsion forces is limited and, thus, treatment of long bones should be considered with caution. In recent years, variant techniques of percutaneous bone consolidation have emerged, including expansion devices for vertebral augmentation and percutaneous screw fixation for pelvic bone and proximal femur tumors. Research projects are ongoing to develop drug-loaded cements to use them as therapeutic vectors. However, release of drugs is still poorly controlled and conventional polymethylmethacrylate cement remains the gold standard in oncology. Image-guided consolidation techniques enhance the array of treatments in bone oncology. Multidisciplinary approach is mandatory to select the best indications.Entities:
Keywords: bone metastasis; cementoplasty; interventional radiology; screw fixation; vertebroplasty
Year: 2018 PMID: 30402004 PMCID: PMC6218251 DOI: 10.1055/s-0038-1669468
Source DB: PubMed Journal: Semin Intervent Radiol ISSN: 0739-9529 Impact factor: 1.513