| Literature DB >> 3040097 |
S Güldütuna, G Zimmer, W Kurtz, U Leuschner.
Abstract
Rat gastric surface cell membranes were prepared and the effect of taurocholic acid assessed by ESR spectroscopy using the 16-doxylstearic acid spin label. Taurocholic acid increased the polar part of the spectra, indicating an augmented amount of spin label molecules with a polar environment. Concomitantly, mobility of the spin label molecule was augmented. The effect of taurocholic acid was completely prevented by the previous addition of prostaglandin E2. This suggests a direct protective efficiency of prostaglandin E2 on rat gastric surface cell membranes without the metabolic participation of intact cells.Entities:
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Year: 1987 PMID: 3040097 DOI: 10.1016/0005-2736(87)90298-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002