Literature DB >> 30397990

A Dual-Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy.

Hongyu Wang1, Jinjie Chang1, Mingwan Shi1, Wei Pan1, Na Li1, Bo Tang1.   

Abstract

The development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual-targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells. The synthesized photothermal agent exhibited high photothermal conversion efficiency, low cytotoxicity, and good biological compatibility. In vivo experiments showed an excellent tumor inhibitory effect of the dual-targeted photothermal agent.
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antitumor agents; cancer treatment; drug delivery; organic photothermal agents; photothermal therapy

Year:  2018        PMID： 30397990     DOI： 10.1002/anie.201811273

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  15 in total

1.  Cell organelle targeting of near-infrared croconaine dye controls photothermal outcome.

Authors:  Ying Wen; Hannah H McGarraugh; Cynthia L Schreiber; Bradley D Smith
Journal:  Chem Commun (Camb)       Date:  2020-06-25       Impact factor: 6.222

2.  Photothermal Response of Polyhydroxy Fullerenes.

Authors:  Alan Chen; Stephen R Grobmyer; Vijay B Krishna
Journal:  ACS Omega       Date:  2020-06-04

3.  Interaction of Immune Cells and Tumor Cells in Gold Nanorod-Gelatin Composite Porous Scaffolds.

Authors:  Xiuhui Wang; Naoki Kawazoe; Guoping Chen
Journal:  Nanomaterials (Basel)       Date:  2019-09-24       Impact factor: 5.076

4.  A stepwise-targeting strategy for the treatment of cerebral ischemic stroke.

Authors:  Jingbo Hu; Xueying Tan; Dongwei Wang; Yixuan Li; Hongze Liang; Jiejun Peng; Fengyan Li; Quan Zhou; Peiwu Geng; Shuanghu Wang; Yue Yu; Jin Liu
Journal:  J Nanobiotechnology       Date:  2021-11-17       Impact factor: 9.429

5.  γ-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy.

Authors:  Fangyuan Zhou; Shikui Yang; Chao Zhao; Wangwang Liu; Xufeng Yao; Hui Yu; Xiaolian Sun; Yi Liu
Journal:  Theranostics       Date:  2021-05-13       Impact factor: 11.556

6.  Paclitaxel/IR1061-Co-Loaded Protein Nanoparticle for Tumor-Targeted and pH/NIR-II-Triggered Synergistic Photothermal-Chemotherapy.

Authors:  Li He; Fangzhen Qing; Maode Li; Daitian Lan
Journal:  Int J Nanomedicine       Date:  2020-04-02

7.  880 nm NIR-Triggered Organic Small Molecular-Based Nanoparticles for Photothermal Therapy of Tumor.

Authors:  Yunying Zhao; Zheng He; Qiang Zhang; Jing Wang; Wenying Jia; Long Jin; Linlin Zhao; Yan Lu
Journal:  Nanomaterials (Basel)       Date:  2021-03-18       Impact factor: 5.076

8.  Precision photothermal therapy and photoacoustic imaging by in situ activatable thermoplasmonics.

Authors:  Yahua Liu; Fengye Mo; Jialing Hu; Qunying Jiang; Xiuyuan Wang; Zhiqiao Zou; Xian-Zheng Zhang; Dai-Wen Pang; Xiaoqing Liu
Journal:  Chem Sci       Date:  2021-06-24       Impact factor: 9.825

9.  Metal organic framework-coated gold nanorod as an on-demand drug delivery platform for chemo-photothermal cancer therapy.

Authors:  Junfeng Huang; Zhourui Xu; Yihang Jiang; Wing-Cheung Law; Biqin Dong; Xierong Zeng; Mingze Ma; Gaixia Xu; Jizhao Zou; Chengbin Yang
Journal:  J Nanobiotechnology       Date:  2021-07-19       Impact factor: 10.435

10.  An Acceptor-π-Donor Structured Organic Chromophore for NIR Triggered Thermal Ablation of Tumor via DNA Damage-Mediated Apoptosis.

Authors:  Di Zhang; Jinghong Yang; Chuang Liu; Sheng Ye; Qianbing Zhang; Ruiyuan Liu
Journal:  Int J Nanomedicine       Date:  2021-07-20
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