Rami Archid1, Nicole Archid2, Tobias Meile3, Jonas Hoffmann2, Julia Hilbert2, Daniel Wulff2, Martin Teufel4,5, Michaela Muthig4, Markus Quante2, Alfred Königsrainer2, Jessica Lange2. 1. Department of General, Visceral and Transplant Surgery, Eberhard-Karls-University Hospital Tuebingen, Hoppe-Seyler-Str. 3-5, 72076, Tübingen, Germany. rami.archid@med.uni-tuebingen.de. 2. Department of General, Visceral and Transplant Surgery, Eberhard-Karls-University Hospital Tuebingen, Hoppe-Seyler-Str. 3-5, 72076, Tübingen, Germany. 3. Department of General, Visceral and Transplant Surgery, Bad Cannstatt Hospital, Stuttgart, Germany. 4. Department of Psychosomatic Medicine and Psychotherapy, Eberhard-Karls-University Hospital Tuebingen, Tübingen, Germany. 5. Clinic for Psychosomatic Medicine and Psychotherapy, University of Duisburg-Essen, LVR Clinic, Essen, Germany.
Abstract
PURPOSE: The aim of this study was to compare surgical and psychiatric outcome and weight loss in schizophrenia patients with mentally healthy patients after sleeve gastrectomy. MATERIALS AND METHODS: A cohort study design was selected, comprising patients with schizophrenia with mentally healthy patients who underwent sleeve gastrectomy and were adherent to a follow-up at least 12 months after surgery. RESULTS: Seven schizophrenia (5 male, 2 female) and 59 (12 male, 47 female) mentally healthy patients were included in this study. A laparoscopic sleeve gastrectomy was performed safely in all 66 patients. The calculated excess weight loss (%EWL) showed no significant differences in both groups and reached 51.68 ± 15.84% for schizophrenia group and 60.68 ± 19.95% for mentally healthy group at 24-month follow-up (p = 0.33). The decrease in the HbA1c levels within 2 years after sleeve gastrectomy was similar in both groups (p = 0.79, 0.88, 0.82, 0.73 for surgery time, time of 6-, 12-, and 24-month follow-up respectively). The psychiatric status of the patients of the schizophrenia group was stable in all cases and no exacerbation of psychiatric symptoms was observed during time of follow-up. Furthermore, an overall significant improvement of the self-estimated mood and satisfaction was observed in both groups (Manova: f = 1.26, p < 0.0001). CONCLUSIONS: The results 2 years after sleeve gastrectomy in stable patients with schizophrenia and after an adequate psychological evaluation were encouraging and comparable to the outcome in mentally healthy patients.
PURPOSE: The aim of this study was to compare surgical and psychiatric outcome and weight loss in schizophreniapatients with mentally healthypatients after sleeve gastrectomy. MATERIALS AND METHODS: A cohort study design was selected, comprising patients with schizophrenia with mentally healthypatients who underwent sleeve gastrectomy and were adherent to a follow-up at least 12 months after surgery. RESULTS: Seven schizophrenia (5 male, 2 female) and 59 (12 male, 47 female) mentally healthypatients were included in this study. A laparoscopic sleeve gastrectomy was performed safely in all 66 patients. The calculated excess weight loss (%EWL) showed no significant differences in both groups and reached 51.68 ± 15.84% for schizophrenia group and 60.68 ± 19.95% for mentally healthy group at 24-month follow-up (p = 0.33). The decrease in the HbA1c levels within 2 years after sleeve gastrectomy was similar in both groups (p = 0.79, 0.88, 0.82, 0.73 for surgery time, time of 6-, 12-, and 24-month follow-up respectively). The psychiatric status of the patients of the schizophrenia group was stable in all cases and no exacerbation of psychiatric symptoms was observed during time of follow-up. Furthermore, an overall significant improvement of the self-estimated mood and satisfaction was observed in both groups (Manova: f = 1.26, p < 0.0001). CONCLUSIONS: The results 2 years after sleeve gastrectomy in stable patients with schizophrenia and after an adequate psychological evaluation were encouraging and comparable to the outcome in mentally healthypatients.
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