Enver Ilhan1, Bakir Bati2, Ali Alemdar2, Ali Coskun1, Arsenal Sezgin3, Mehmet Yildirim1, Omer Engin1, Mete Purten1. 1. Department of General Surgery, Izmir Bozyaka Education and Research Hospital, Turkey. 2. Department of General Surgery, Istanbul Okmeydani Education and Research Hospital, Turkey. 3. Department of Pathology, Izmir Bozyaka Education and Research Hospital, Turkey.
Abstract
BACKGROUND: Although male breast cancer constitutes only 1% of all breast cancers, its incidence is increasing and it is becoming an important public health issue. The present study aims to present the clinicopathological characteristics of surgically treated male breast cancer patients from multiple centers. PATIENTS AND METHODS: Twenty-one male patients operated on for breast cancer were retrospectively examined in terms of clinical presentation, pathological characteristics, TNM staging status, and type of surgical treatment. RESULTS: The mean age of the 21 patients was 62.3 years (range 38-94), with the majority being in the range of 50-69 years (61.9%). The most frequent finding was breast mass (85.7%). Most patients underwent modified radical mastectomy (76.1%), and the most prevalent histological type was invasive ductal carcinoma (85.7%). The majority of patients had stage II or III disease, and estrogen receptors were positive in 18 (85.7%) of the patients. CONCLUSION: Since male breast cancer is a rare condition, it is challenging to conduct prospective randomized trials. Currently, there is a lack of comprehensive data on the diagnosis and management of this condition. Thus, further studies and the implementation of specific guidelines or protocols for this subgroup of patients will aid better management.
BACKGROUND: Although male breast cancer constitutes only 1% of all breast cancers, its incidence is increasing and it is becoming an important public health issue. The present study aims to present the clinicopathological characteristics of surgically treated male breast cancer patients from multiple centers. PATIENTS AND METHODS: Twenty-one male patients operated on for breast cancer were retrospectively examined in terms of clinical presentation, pathological characteristics, TNM staging status, and type of surgical treatment. RESULTS: The mean age of the 21 patients was 62.3 years (range 38-94), with the majority being in the range of 50-69 years (61.9%). The most frequent finding was breast mass (85.7%). Most patients underwent modified radical mastectomy (76.1%), and the most prevalent histological type was invasive ductal carcinoma (85.7%). The majority of patients had stage II or III disease, and estrogen receptors were positive in 18 (85.7%) of the patients. CONCLUSION: Since male breast cancer is a rare condition, it is challenging to conduct prospective randomized trials. Currently, there is a lack of comprehensive data on the diagnosis and management of this condition. Thus, further studies and the implementation of specific guidelines or protocols for this subgroup of patients will aid better management.
Entities:
Keywords:
Breast cancer; Male breast cancer; Neoplasm
Authors: Judy C Boughey; Isabelle Bedrosian; Funda Meric-Bernstam; Merrick I Ross; Henry M Kuerer; Jeri S Akins; Sharon H Giordano; Gildy V Babiera; Frederick C Ames; Kelly K Hunt Journal: J Am Coll Surg Date: 2006-08-23 Impact factor: 6.113
Authors: B Cutuli; M Lacroze; J M Dilhuydy; M Velten; B De Lafontan; C Marchal; M Resbeut; Y Graic; F Campana; V Moncho-Bernier Journal: Eur J Cancer Date: 1995-11 Impact factor: 9.162