Literature DB >> 30396636

Variability in Partial Nephrectomy Outcomes: Does Your Surgeon Matter?

Julien Dagenais1, Riccardo Bertolo1, Juan Garisto1, Matthew J Maurice1, Pascal Mouracade1, Onder Kara1, Jaya Chavali1, Jianbo Li2, Ryan Nelson1, Amr Fergany1, Robert Abouassaly1, Jihad H Kaouk3.   

Abstract

BACKGROUND: Understanding physician-level discrepancies is increasingly a target of US healthcare reform for the delivery of quality-focused patient care.
OBJECTIVE: To estimate the relative contributions of patient and surgeon characteristics to the variability in key outcomes after partial nephrectomy (PN). DESIGN, SETTING, AND PARTICIPANTS: Retrospective review of 1461 patients undergoing PN performed by 19 surgeons between 2011 and 2016 at a tertiary care referral center. INTERVENTION: PN for a renal mass. OUTCOMES MEASUREMENTS AND STATISTICAL ANALYSIS: Hierarchical linear and logistic regression models were built to determine the percentage variability contributed by fixed patient and surgeon factors on peri- and postoperative outcomes. Residual between- and within-surgeon variability was calculated while adjusting for fixed factors. RESULTS AND LIMITATIONS: On null hierarchical models, there was significant between-surgeon variability in operative time, estimated blood loss (EBL), ischemia time, excisional volume loss, length of stay, positive margins, Clavien complications, and 30-d readmission rate (all p<0.001), but not chronic kidney disease upstaging (p=0.47) or percentage preservation of glomerular filtration rate (p=0.49). Patient factors explained 82% of the variability in excisional volume loss and 0-32% of the variability in the remainder of outcomes. Quantifiable surgeon factors explained modest amounts (10-40%) of variability in intraoperative outcomes, and noteworthy amounts of variability (90-100%) in margin rates and patient morbidity outcomes. Immeasurable surgeon factors explained the residual variability in operative time (27%), EBL (6%), and ischemia time (31%).
CONCLUSIONS: There is significant between-surgeon variability in outcomes after PN, even after adjusting for patient characteristics. While renal functional outcomes are consistent across surgeons, measured and unmeasured surgeon factors account for 18-100% of variability of the remaining peri- and postoperative variables. With the increasing utilization of value-based medicine, this has important implications for the goal of optimizing patient care. PATIENT
SUMMARY: We reviewed our institutional database on partial nephrectomy performed for renal cancer. We found significant variability between surgeons for key outcomes after the intervention, even after adjusting for patient characteristics.
Copyright © 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Complications; Nephron sparing; Outcomes; Partial nephrectomy; Renal neoplasm; Surgeon

Mesh:

Year:  2018        PMID: 30396636     DOI: 10.1016/j.eururo.2018.10.046

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  12 in total

1.  Renal function after kidney surgery: "it's tough to make predictions, especially about the future".

Authors:  John M DiBianco; Patrick T Gomella; Mark W Ball
Journal:  Ann Transl Med       Date:  2019-07

2.  Are nephrometry scores enough to select patients really fit for nephron sparing surgery?

Authors:  Francesco Porpiglia; Daniele Amparore; Angela Pecoraro; Enrico Checcucci
Journal:  Ann Transl Med       Date:  2019-09

3.  Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer-UROCCR 58-NCT03293563.

Authors:  Adil Mellouki; Imad Bentellis; Arnoult Morrone; Nicolas Doumerc; Jean-Baptiste Beauval; Morgane Roupret; François-Xavier Nouhaud; Cedric Lebacle; Jean-Alexandre Long; Daniel Chevallier; Brannwel Tibi; Aysha Shaikh; L Imbert de la Phalecque; Pierre Pillot; Xavier Tillou; Jean-Christophe Bernhard; Matthieu Durand; Youness Ahallal
Journal:  World J Urol       Date:  2021-02-19       Impact factor: 4.226

Review 4.  Is There a Surgeons' Effect on Patients' Physical Health, Beyond the Intervention, That Requires Further Investigation? A Systematic Review.

Authors:  Christoph Schnelle; Justin Clark; Rachel Mascord; Mark A Jones
Journal:  Ther Clin Risk Manag       Date:  2022-04-26       Impact factor: 2.755

5.  Editorial Comment to Randomized trials to determine the ideal management of the renal artery during partial nephrectomy: Life's under no obligation to give us what we expect.

Authors:  Riccardo Campi; Daniele Amparore
Journal:  Int J Urol       Date:  2021-11-05       Impact factor: 2.896

6.  'Trifecta' outcomes of robot-assisted partial nephrectomy: Results of the 'low volume' surgeon.

Authors:  Cem Basatac; Haluk Akpinar
Journal:  Int Braz J Urol       Date:  2020 Nov-Dec       Impact factor: 1.541

7.  Learning curve in robot-assisted partial nephrectomy: comparison between an expert surgeon and a team in training in single-center experiences.

Authors:  Nicolò Fiorello; Andrea Di Benedetto; Daniele Summonti; Andrea Mogorovich; Carlo Alberto Sepich
Journal:  Cent European J Urol       Date:  2021-12-06

8.  Development and validation of an integrated nomogram to predict personalized new baseline functional outcomes after partial nephrectomy.

Authors:  Dachun Jin; Yong Luo; Hailin Zhu; Yaoming Li; Zaoming Huang; Yao Zhang; Jun Zhang; Jun Jiang
Journal:  Transl Androl Urol       Date:  2022-01

9.  Predictors of Positive Surgical Margins after Robot-Assisted Partial Nephrectomy for Localized Renal Tumors: Insights from a Large Multicenter International Prospective Observational Project (The Surface-Intermediate-Base Margin Score Consortium).

Authors:  Fabrizio Di Maida; Riccardo Campi; Brian R Lane; Ottavio De Cobelli; Francesco Sanguedolce; Georgios Hatzichristodoulou; Alessandro Antonelli; Antonio Andrea Grosso; Sabrina Noyes; Oscar Rodriguez-Faba; Frank X Keeley; Johan Langenhuijsen; Gennaro Musi; Tobias Klatte; Marco Roscigno; Bulent Akdogan; Maria Furlan; Claudio Simeone; Nihat Karakoyunlu; Martin Marszalek; Umberto Capitanio; Alessandro Volpe; Sabine Brookman-May; Jürgen E Gschwend; Marc C Smaldone; Robert G Uzzo; Alexander Kutikov; Andrea Minervini
Journal:  J Clin Med       Date:  2022-03-23       Impact factor: 4.241

10.  Partial Nephrectomy, a Comparison between Different Modalities: A Tertiary Care Center Experience.

Authors:  Ahmed Al Asker; Abdulmalik Addar; Mohammed Alghamdi; Saud Alawad; Mohammed Alharbi; Saeed Bin Hamri; Nasser Albqami; Abdullah Alkhayal; Khaled Alrabeeah
Journal:  J Kidney Cancer VHL       Date:  2021-06-17
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