Literature DB >> 30396627

The effect of Cinnamon on primary dysmenorrhea: A randomized, double-blind clinical trial.

Maryam Jahangirifar1, Mahboubeh Taebi2, Mahrokh Dolatian3.   

Abstract

BACKGROUND: Primary dysmenorrhea is a cyclic cramp in pelvic which interferes with daily activity. This study determined the effect of Cinnamon on relieving dysmenorrhea.
METHODS: This is a randomized, double-blind clinical trial. The intervention group received Cinnamon (capsules contained 1000 mg cinnamon) and the control group received placebo (capsules contained 1000 mg starch) during the first 72 h of menstruation for two cycles continuously. The Visual Analogue Scale was used to determine the severity of pain. The subjects were followed up for two cycles. Descriptive statistics, Independent T test, analysis of variance (ANOVA) with repeated measures were used for continuous quantitative variables. Mann-Whitney and Chi-square tests were used for nominal and ordinal qualitative variables.
RESULTS: The results showed the mean intensity of dysmenorrhea significantly decreased over time in both groups (time: P < 0.001) and this reduction was significantly different over time between two groups (time*group: P = 0.02). There is significantly more reduction in the intervention group. Also the pain reduction in the intervention group was significantly lower than the placebo group after the first treatment (P = 0.001) and the second treatment (P = 0.002) compared to before treatment.
CONCLUSIONS: Cinnamon can reduce the intensity of primary dysmenorrhea. This aromatic spice for relive of primary dysmenorrhea is recommended.
Copyright © 2018. Published by Elsevier Ltd.

Entities:  

Keywords:  Cinnamon; Clinical trial; Herbal medicine; Primary dysmenorrhea

Mesh:

Substances:

Year:  2018        PMID: 30396627     DOI: 10.1016/j.ctcp.2018.08.001

Source DB:  PubMed          Journal:  Complement Ther Clin Pract        ISSN: 1744-3881            Impact factor:   2.446


  7 in total

1.  Involvement of a neutrophil-mast cell axis in the effects of Piper malacophyllum (C. PESL) C. DC extract and its isolated compounds in a mouse model of dysmenorrhoea.

Authors:  Nara Lins Meira Quintão; Jaqueline Pavesi Reis; Larissa Benvenutti; Roberta Nunes; Fernanda Capitanio Goldoni; Manuela Somensi Cozer; Priscila de Souza; Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva; Jessica Melato; Carlos Rafael Vaz; Juliana Cristina Pereira Whitaker; Flavia Werner Jesuíno; Mariana Couto Costa; Maria Verônica Dávila Pastor; Angela Malheiros; Christiane Meyre-Silva; José Roberto Santin
Journal:  Inflammopharmacology       Date:  2022-07-22       Impact factor: 5.093

2.  Thyme Tea and Primary Dysmenorrhea Among Young Female Students.

Authors:  Abayneh Birlie Zeru; Mikyas Arega Muluneh
Journal:  Adolesc Health Med Ther       Date:  2020-10-20

3.  Cinnamon and Hop Extracts as Potential Immunomodulators for Severe COVID-19 Cases.

Authors:  Kurt Lucas; Janine Fröhlich-Nowoisky; Nicole Oppitz; Maximilian Ackermann
Journal:  Front Plant Sci       Date:  2021-02-26       Impact factor: 5.753

4.  Efficacy of herbal medicine (cinnamon/fennel/ginger) for primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Yincong Xu; Qinglin Yang; Xiaoping Wang
Journal:  J Int Med Res       Date:  2020-06       Impact factor: 1.671

Review 5.  Integrating Lifestyle Focused Approaches into the Management of Primary Dysmenorrhea: Impact on Quality of Life.

Authors:  Orestis Tsonis; Fani Gkrozou; Zoi Barmpalia; Annamaria Makopoulou; Vassiliki Siafaka
Journal:  Int J Womens Health       Date:  2021-03-17

Review 6.  Safety of Cinnamon: An Umbrella Review of Meta-Analyses and Systematic Reviews of Randomized Clinical Trials.

Authors:  Dan-Tong Gu; Tao-Hsin Tung; Zhu Liduzi Jiesisibieke; Ching-Wen Chien; Wen-Yi Liu
Journal:  Front Pharmacol       Date:  2022-01-18       Impact factor: 5.810

7.  Assessment of clinical efficacy of traditional Chinese medicine for the management of primary dysmenorrhea in the UK: A protocol of systematic review.

Authors:  Ming-Ming Fu; Xiang-Dong Meng
Journal:  Medicine (Baltimore)       Date:  2020-11-20       Impact factor: 1.817

  7 in total

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