Literature DB >> 30394930

Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases.

Paola M Perez1, Thomas A Hope1, Spencer C Behr1, Annemieke van Zante2, Eric J Small3, Robert R Flavell1.   

Abstract

We present a case of a 61-year-old man with history of prostate cancer and rising PSA levels referred for restaging. Ga-PSMA-11 PET/CT identified 2 lung nodules with low and moderate PSMA uptake. Subsequent F-FDG PET/CT showed high hypermetabolism in the nodule with low PSMA uptake, and low hypermetabolism in the nodule with moderate PSMA uptake. The isolated pulmonary findings and metabolic appearance is an atypical presentation of prostate cancer metastases and raised concern for a second primary malignancy. Fine-needle aspiration of the F-FDG active lung nodule confirmed metastatic prostatic adenocarcinoma that subsequently responded to androgen deprivation therapy and abiraterone acetate.

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Year:  2019        PMID： 30394930     DOI： 10.1097/RLU.0000000000002367

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  7 in total

1.  Diagnostic value of 18F-FDG PET/CT in patients with biochemical recurrent prostate cancer and negative 68Ga-PSMA PET/CT.

Authors:  Ruohua Chen; Yining Wang; Yiping Shi; Yinjie Zhu; Lian Xu; Gang Huang; Jianjun Liu
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-02-02       Impact factor: 9.236

2.  Multitarget Molecular Imaging in Metastatic Castration Resistant Adenocarcinoma Prostate Cancer with Therapy Induced Neuroendocrine Differentiation.

Authors:  Joel Vargas Ahumada; Sofía D González Rueda; Fabio A Sinisterra Solís; Quetzali Pitalúa Cortés; Liliana P Torres Agredo; Jimenez Ríos Miguel; Anna Scavuzzo; Irma Soldevilla-Gallardo; Miguel A Álvarez Avitia; Nora Sobrevilla; Francisco Osvaldo García Pérez
Journal:  Diagnostics (Basel)       Date:  2022-06-03

3.  The Added Value of 18F-FDG PET/CT Compared with 68Ga-PSMA PET/CT in Patients with Castration-Resistant Prostate Cancer.

Authors:  Ruohua Chen; Yining Wang; Yinjie Zhu; Yiping Shi; Lian Xu; Gang Huang; Jianjun Liu
Journal:  J Nucl Med       Date:  2022-01       Impact factor: 11.082

4.  Use of 68Ga-PSMA-11 and 18F-FDG PET-CT Dual-Tracer to Differentiate Between Lymph Node Metastases and Ganglia.

Authors:  Yiping Shi; Lian Xu; Yinjie Zhu; Yining Wang; Ruohua Chen; Jianjun Liu
Journal:  Front Oncol       Date:  2021-03-10       Impact factor: 6.244

5.  The Heterogeneous Metabolic Patterns of Ganglia in 68Ga-PSMA, 11C-choline, and 18F-FDG PET/CT in Prostate Cancer Patients.

Authors:  Yiping Shi; Jian Guo Wu; Lian Xu; Yinjie Zhu; Yining Wang; Gan Huang; Jianjun Liu; Ruohua Chen
Journal:  Front Oncol       Date:  2021-04-23       Impact factor: 6.244

6.  Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors.

Authors:  Martin K Bakht; Jessica M Lovnicki; Janice Tubman; Keith F Stringer; Jonathan Chiaramonte; Michael R Reynolds; Iulian Derecichei; Rosa-Maria Ferraiuolo; Bre-Anne Fifield; Dorota Lubanska; So Won Oh; Gi Jeong Cheon; Cheol Kwak; Chang Wook Jeong; Keon Wook Kang; John F Trant; Colm Morrissey; Ilsa M Coleman; Yuzhuo Wang; Hojjat Ahmadzadehfar; Xuesen Dong; Lisa A Porter
Journal:  J Nucl Med       Date:  2019-12-05       Impact factor: 11.082

Review 7.  More Than Meets the Eye: Scientific Rationale behind Molecular Imaging and Therapeutic Targeting of Prostate-Specific Membrane Antigen (PSMA) in Metastatic Prostate Cancer and Beyond.

Authors:  Anniina Hyväkkä; Verneri Virtanen; Jukka Kemppainen; Tove J Grönroos; Heikki Minn; Maria Sundvall
Journal:  Cancers (Basel)       Date:  2021-05-07       Impact factor: 6.639
  7 in total

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