Philippe Martin1, Claire Nour Abou Chakra1, Victoria Williams2, Kathryn Bush3, Myrna Dyck4, Zahir Hirji5, Alex Kiss6, Oscar E Larios7, Allison McGeer8, Christine Moore9, Karl Weiss10, Andrew E Simor2. 1. 1Department of Microbiology and Infectious Disease,Université de Sherbrooke,Sherbrooke,Quebec,Canada. 2. 2Sunnybrook Health Sciences Centre,Toronto,Ontario,Canada. 3. 4Alberta Health Services,Calgary,Alberta,Canada. 4. 5Winnipeg Regional Health Authority,Winnipeg,Manitoba,Canada. 5. 6The Scarborough Hospital,Toronto,Ontario,Canada. 6. 7Institute of Clinical Evaluative Sciences,Toronto,Ontario,Canada. 7. 8University of Calgary,Calgary,Alberta,Canada. 8. 3University of Toronto,Toronto,Ontario,Canada. 9. 9Mount Sinai Hospital,Toronto,Ontario,Canada. 10. 10Jewish General Hospital,Montreal,Quebec,Canada.
Abstract
OBJECTIVE: Point-prevalence surveys for infection or colonization with methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae (CREs), and for Clostridium difficile infection (CDI) were conducted in Canadian hospitals in 2010 and 2012 to better understanding changes in the epidemiology of antimicrobial-resistant organisms (AROs), which is crucial for public health and care management. METHODS: A third survey of the same AROs in adult inpatients in Canadian hospitals with ≥50 beds was performed in February 2016. Data on participating hospitals and patient cases were obtained using standard criteria and case definitions. Associations between ARO prevalence and institutional characteristics were assessed using logistic regression models. RESULTS: In total, 160 hospitals from 9 of the 10 provinces with 35,018 adult inpatients participated in the survey. Median prevalence per 100 inpatients was 4.1 for MRSA, 0.8 for VRE, 1.1 for CDI, 0.8 for ESBLs, and 0 for CREs. No significant change occurred compared to 2012. CREs were reported from 24 hospitals (15%) in 2016 compared to 10 hospitals (7%) in 2012. Routine universal or targeted admission screening for VRE decreased from 94% in 2010 to 74% in 2016. Targeted screening for MRSA on admission was associated with a lower prevalence of MRSA infection. Large hospitals (>500 beds) had higher prevalences of CDI. CONCLUSION: This survey provides national prevalence rates for AROs in Canadian hospitals. Changes in infection control and prevention policies might lead to changes in the epidemiology of AROs and our capacity to detect them.
OBJECTIVE: Point-prevalence surveys for infection or colonization with methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae (CREs), and for Clostridium difficile infection (CDI) were conducted in Canadian hospitals in 2010 and 2012 to better understanding changes in the epidemiology of antimicrobial-resistant organisms (AROs), which is crucial for public health and care management. METHODS: A third survey of the same AROs in adult inpatients in Canadian hospitals with ≥50 beds was performed in February 2016. Data on participating hospitals and patient cases were obtained using standard criteria and case definitions. Associations between ARO prevalence and institutional characteristics were assessed using logistic regression models. RESULTS: In total, 160 hospitals from 9 of the 10 provinces with 35,018 adult inpatients participated in the survey. Median prevalence per 100 inpatients was 4.1 for MRSA, 0.8 for VRE, 1.1 for CDI, 0.8 for ESBLs, and 0 for CREs. No significant change occurred compared to 2012. CREs were reported from 24 hospitals (15%) in 2016 compared to 10 hospitals (7%) in 2012. Routine universal or targeted admission screening for VRE decreased from 94% in 2010 to 74% in 2016. Targeted screening for MRSA on admission was associated with a lower prevalence of MRSA infection. Large hospitals (>500 beds) had higher prevalences of CDI. CONCLUSION: This survey provides national prevalence rates for AROs in Canadian hospitals. Changes in infection control and prevention policies might lead to changes in the epidemiology of AROs and our capacity to detect them.
Authors: Daleen Loest; F Carl Uhland; Kaitlin M Young; Xian-Zhi Li; Michael R Mulvey; Richard Reid-Smith; Lauren M Sherk; Carolee A Carson Journal: Epidemiol Infect Date: 2022-06-29 Impact factor: 4.434
Authors: Ziad W Jaradat; Qutaiba O Ababneh; Sherin T Sha'aban; Ayesha A Alkofahi; Duaa Assaleh; Anan Al Shara Journal: Pathog Glob Health Date: 2020-10-28 Impact factor: 2.894
Authors: Charles Frenette; David Sperlea; Greg J German; Kevin Afra; Jennifer Boswell; Sandra Chang; Herman Goossens; Jennifer Grant; Marie-Astrid Lefebvre; Allison McGeer; Dominic Mertz; Michelle Science; Ann Versporten; Daniel J G Thirion Journal: Antimicrob Resist Infect Control Date: 2020-07-11 Impact factor: 4.887