Literature DB >> 30394116

Outcomes of emergency neurosurgical intervention in neuro-critical care patients with traumatic brain injury at Cork University Hospital.

Michael Amoo1, Philip J O'Halloran1, Anne-Marie Leo2, Aoife O'Loughlin2, Padraig Mahon2, Chris Lim1.   

Abstract

Traumatic Brain Injury (TBI) is a major cause of death and disability; the leading cause of mortality and morbidity in previously healthy people aged under 40 in the United Kingdom (UK). There are currently little official Irish statistics regarding TBI or outcome measures following TBI, although it is estimated that over 2000 people per year sustain TBI in Ireland. We performed a retrospective cohort study of TBI patients who were managed in the intensive care unit (ICU) at CUH between July 2012 and December 2015. Demographic data were compiled by patients' charts reviews. Using the validated Glasgow outcome scale extended (GOS-E) outcome measure tool, we interviewed patients and/or their carers to measure functional outcomes. Descriptive statistical analyses were performed. Spearman's correlation analysis was used to assess association between different variables using IBM's Statistical Package for the Social Sciences (SPSS) 20. In the 42-month period, 102 patients were identified, mainly males (81%). 49% had severe TBI and 56% were referred from other hospitals. The mean age was 44.7 and a most of the patients were previously healthy, with 65% of patients having ASA I or II. Falls accounted for the majority of the TBI, especially amongst those aged over 50. The 30-day mortality was 25.5% and the mean length of hospital stay (LOS-H) was 33 days. 9.8% of the study population had a good recovery (GOS-E 8), while 7.8% had a GOS-E score of 3 (lower sever disability). Patients with Extra-Dural haemorrhage had better outcomes compared with those with SDH or multi-compartmental haemorrhages (p = 0.007). Older patients had a higher mortality, with the highest mortality (37.5%) among those over 50 years old (p = 0.009). TBI is associated with significant morbidity and mortality. Despite the young mean age and low ASA the mortality, morbidity and average LOS-H were significant, highlighting the health and socioeconomic burden of TBI.

Entities:  

Keywords:  Glasgow outcome scale extended; disability; intensive care unit; traumatic brain injury

Mesh:

Year:  2018        PMID: 30394116     DOI: 10.1080/02688697.2018.1522416

Source DB:  PubMed          Journal:  Br J Neurosurg        ISSN: 0268-8697            Impact factor:   1.596


  2 in total

Review 1.  Traumatic Brain Injury and Blood-Brain Barrier (BBB): Underlying Pathophysiological Mechanisms and the Influence of Cigarette Smoking as a Premorbid Condition.

Authors:  Farzane Sivandzade; Faleh Alqahtani; Luca Cucullo
Journal:  Int J Mol Sci       Date:  2020-04-14       Impact factor: 5.923

2.  The impact of COVID-19 on trauma referrals to a National Neurosurgical Centre.

Authors:  Jack Horan; John C Duddy; Brian Gilmartin; Michael Amoo; Deirdre Nolan; Paula Corr; Mohammed Ben Husien; Ciaran Bolger
Journal:  Ir J Med Sci       Date:  2021-01-07       Impact factor: 2.089

  2 in total

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