Literature DB >> 30393443

Ground states in the diffusion-dominated regime.

José A Carrillo1, Franca Hoffmann2, Edoardo Mainini3, Bruno Volzone4.   

Abstract

We consider macroscopic descriptions of particles where repulsion is modelled by non-linear power-law diffusion and attraction by a homogeneous singular kernel leading to variants of the Keller-Segel model of chemotaxis. We analyse the regime in which diffusive forces are stronger than attraction between particles, known as the diffusion-dominated regime, and show that all stationary states of the system are radially symmetric non-increasing and compactly supported. The model can be formulated as a gradient flow of a free energy functional for which the overall convexity properties are not known. We show that global minimisers of the free energy always exist. Further, they are radially symmetric, compactly supported, uniformly bounded and C ∞ inside their support. Global minimisers enjoy certain regularity properties if the diffusion is not too slow, and in this case, provide stationary states of the system. In one dimension, stationary states are characterised as optimisers of a functional inequality which establishes equivalence between global minimisers and stationary states, and allows to deduce uniqueness.

Entities:  

Keywords:  35K55; 35K65; 49K20

Year:  2018        PMID: 30393443      PMCID: PMC6190998          DOI: 10.1007/s00526-018-1402-2

Source DB:  PubMed          Journal:  Calc Var Partial Differ Equ        ISSN: 0944-2669            Impact factor:   1.945


  7 in total

1.  Mathematical modelling of cancer cell invasion of tissue: local and non-local models and the effect of adhesion.

Authors:  A Gerisch; M A J Chaplain
Journal:  J Theor Biol       Date:  2008-02-21       Impact factor: 2.691

2.  Mathematical modelling of cancer invasion: implications of cell adhesion variability for tumour infiltrative growth patterns.

Authors:  Pia Domschke; Dumitru Trucu; Alf Gerisch; Mark A J Chaplain
Journal:  J Theor Biol       Date:  2014-07-24       Impact factor: 2.691

3.  Continuous models for cell-cell adhesion.

Authors:  Hideki Murakawa; Hideru Togashi
Journal:  J Theor Biol       Date:  2015-03-27       Impact factor: 2.691

4.  A Nonlocal Model for Contact Attraction and Repulsion in Heterogeneous Cell Populations.

Authors:  K J Painter; J M Bloomfield; J A Sherratt; A Gerisch
Journal:  Bull Math Biol       Date:  2015-05-12       Impact factor: 1.758

5.  Chemotaxis, signal relaying and aggregation morphology.

Authors:  V Nanjundiah
Journal:  J Theor Biol       Date:  1973-11-05       Impact factor: 2.691

6.  Model for chemotaxis.

Authors:  E F Keller; L A Segel
Journal:  J Theor Biol       Date:  1971-02       Impact factor: 2.691

7.  Initiation of slime mold aggregation viewed as an instability.

Authors:  E F Keller; L A Segel
Journal:  J Theor Biol       Date:  1970-03       Impact factor: 2.691

  7 in total

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