Literature DB >> 30393406

HIGHLY STEREOSELECTIVE REDUCTION OF α-KETO ESTERS: UTILITY OF CIS-1-ARYLSULFONAMIDO-2-INDANOLS AS CHIRAL AUXILIARIES.

Arun K Ghosh1, Yan Chen1.   

Abstract

The reduction of α-keto esters bearing cis-1-arylsulfonamido-2-indanol derivatives proceeded with high diastereoselectivities providing the corresponding α-hydroxy esters in excellent yields. The chiral auxiliary group is removed under mild basic conditions and recovered.

Entities:  

Year:  2000        PMID: 30393406      PMCID: PMC6214205          DOI: 10.1016/0040-4039(95)01385-U

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN: 0040-4039            Impact factor:   2.415


  2 in total

1.  Highly Enantioselective Aldol Reaction: Development of a New Chiral Auxiliary from cis-1-Amino-2-hydroxyindan.

Authors:  Arun K Ghosh; Tien T Duong; Sean P McKee
Journal:  J Chem Soc Chem Commun       Date:  1992

2.  Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates.

Authors:  D O Kiesewetter; J V Silverton; W C Eckelman
Journal:  J Med Chem       Date:  1995-05-12       Impact factor: 7.446

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.