Literature DB >> 30392618

The Role of Precision Medicine in Child Psychiatry: What Can We Expect and When?

Jonathan Posner1.   

Abstract

In the United States, nearly 1 in 5 adults and 1 in 4 children suffer with a mental illness, and for most, these illnesses confer significant social, occupational, or academic impairment.1,2 Whereas considerable progress has been made toward diminishing the impact of mental illness, in the last few decades, advances toward new, more effective, and more refined psychiatric treatments have slowed. First-line medications for depression, schizophrenia, bipolar disorder, and attention-deficit/hyperactivity disorder (ADHD) were all introduced decades ago,3-6 and little progress has been made in augmenting their effectiveness.7,8.
Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 30392618      PMCID: PMC7875186          DOI: 10.1016/j.jaac.2018.07.874

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN: 0890-8567            Impact factor:   8.829


  18 in total

Review 1.  Pediatric cancer research from past successes through collaboration to future transdisciplinary research.

Authors:  Gregory H Reaman
Journal:  J Pediatr Oncol Nurs       Date:  2004 May-Jun       Impact factor: 1.636

2.  An open-label, dose-ranging study of atomoxetine in children with attention deficit hyperactivity disorder.

Authors:  T Spencer; J Biederman; J Heiligenstein; T Wilens; D Faries; J Prince; S V Faraone; J Rea; J Witcher; S Zervas
Journal:  J Child Adolesc Psychopharmacol       Date:  2001       Impact factor: 2.576

3.  The NIMH experimental medicine initiative.

Authors:  Thomas R Insel
Journal:  World Psychiatry       Date:  2015-06       Impact factor: 49.548

4.  Revolution stalled.

Authors:  Steven E Hyman
Journal:  Sci Transl Med       Date:  2012-10-10       Impact factor: 17.956

5.  Participation in pediatric oncology research protocols: Racial/ethnic, language and age-based disparities.

Authors:  Paula Aristizabal; Jenelle Singer; Renee Cooper; Kristen J Wells; Jesse Nodora; Mehrzad Milburn; Sheila Gahagan; Deborah E Schiff; Maria E Martinez
Journal:  Pediatr Blood Cancer       Date:  2015-03-08       Impact factor: 3.167

Review 6.  A history of antipsychotic drug development.

Authors:  W W Shen
Journal:  Compr Psychiatry       Date:  1999 Nov-Dec       Impact factor: 3.735

7.  The promise and challenges of drug repurposing in psychiatry.

Authors:  Maurizio Fava
Journal:  World Psychiatry       Date:  2018-02       Impact factor: 49.548

Review 8.  Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors.

Authors:  Deepika Suri; Cátia M Teixeira; Martha K Caffrey Cagliostro; Darshini Mahadevia; Mark S Ansorge
Journal:  Neuropsychopharmacology       Date:  2014-09-02       Impact factor: 7.853

Review 9.  Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms.

Authors:  Eduardo F Gallo; Jonathan Posner
Journal:  Lancet Psychiatry       Date:  2016-05-13       Impact factor: 27.083

10.  Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.

Authors:  George D Demetri; Margaret von Mehren; Charles D Blanke; Annick D Van den Abbeele; Burton Eisenberg; Peter J Roberts; Michael C Heinrich; David A Tuveson; Samuel Singer; Milos Janicek; Jonathan A Fletcher; Stuart G Silverman; Sandra L Silberman; Renaud Capdeville; Beate Kiese; Bin Peng; Sasa Dimitrijevic; Brian J Druker; Christopher Corless; Christopher D M Fletcher; Heikki Joensuu
Journal:  N Engl J Med       Date:  2002-08-15       Impact factor: 91.245

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  8 in total

1.  Predicting Trajectories of Risk or Resilience in Traumatized Youth.

Authors:  Ran Barzilay
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2020-05

2.  Genetic Studies of Mental Illness: Are Children Being Left Behind?

Authors:  Jonathan Posner; Dominik Biezonski; Sarah Pieper; Cristiane S Duarte
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2020-12-29       Impact factor: 8.829

Review 3.  Four Actionable Bottlenecks and Potential Solutions to Translating Psychiatric Genetics Research: An Expert Review.

Authors:  Jessica L Bourdon; Rachel A Davies; Elizabeth C Long
Journal:  Public Health Genomics       Date:  2020-11-04       Impact factor: 2.000

Review 4.  Attention-deficit hyperactivity disorder.

Authors:  Jonathan Posner; Guilherme V Polanczyk; Edmund Sonuga-Barke
Journal:  Lancet       Date:  2020-01-23       Impact factor: 202.731

5.  Individualized Drugs' Selection by Evaluation of Drug Properties, Pharmacogenomics and Clinical Parameters: Performance of a Bioinformatic Tool Compared to a Clinically Established Counselling Process.

Authors:  Marina Borro; Giovanna Gentile; Sally H Preissner; Leda Marina Pomes; Björn-Oliver Gohlke; Antonio Del Casale; Andreas Eckert; Paolo Marchetti; Saskia Preissner; Robert Preissner; Maurizio Simmaco
Journal:  Pharmgenomics Pers Med       Date:  2021-08-05

Review 6.  European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part III: pharmacological treatment.

Authors:  Veit Roessner; Heike Eichele; Jeremy S Stern; Liselotte Skov; Renata Rizzo; Nanette Mol Debes; Péter Nagy; Andrea E Cavanna; Cristiano Termine; Christos Ganos; Alexander Münchau; Natalia Szejko; Danielle Cath; Kirsten R Müller-Vahl; Cara Verdellen; Andreas Hartmann; Aribert Rothenberger; Pieter J Hoekstra; Kerstin J Plessen
Journal:  Eur Child Adolesc Psychiatry       Date:  2021-11-10       Impact factor: 4.785

Review 7.  Treatment biomarkers for ADHD: Taking stock and moving forward.

Authors:  Giorgia Michelini; Luke J Norman; Philip Shaw; Sandra K Loo
Journal:  Transl Psychiatry       Date:  2022-10-12       Impact factor: 7.989

8.  Network Analysis-Based Disentanglement of the Symptom Heterogeneity in Asian Patients with Schizophrenia: Findings from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics.

Authors:  Joonho Choi; Hyung-Jun Yoon; Jae Hong Park; Yukako Nakagami; Chika Kubota; Toshiya Inada; Takahiro A Kato; Shu-Yu Yang; Sih-Ku Lin; Mian-Yoon Chong; Ajit Avasthi; Sandeep Grover; Roy Abraham Kallivayalil; Andi Jaylangkara Tanra; Kok Yoon Chee; Yu-Tao Xiang; Kang Sim; Afzal Javed; Chay Hoon Tan; Norman Sartorius; Shigenobu Kanba; Naotaka Shinfuku; Yong Chon Park; Seon-Cheol Park
Journal:  J Pers Med       Date:  2022-01-03
  8 in total

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