María Carolina Silva1,2, Alvaro Sepúlveda-Martínez1, Rodolfo Guíñez1, María Teresa Haye2,3, Mauro Parra-Cordero4,5. 1. Department of Obstetrics and Gynecology, Fetal Medicine Unit, Hospital Clínico Universidad de Chile, Santiago, Chile. 2. Maternal and Fetal Medicine Unit, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago, Chile. 3. Department of Obstetrics and Gynecology, Fetal Medicine Unit, Hospital San José, Santiago, Chile. 4. Department of Obstetrics and Gynecology, Fetal Medicine Unit, Hospital Clínico Universidad de Chile, Santiago, Chile, mcparra@hcuch.cl. 5. Department of Obstetrics and Gynecology, Fetal Medicine Unit, Hospital Clínico San Borja Arriarán, Santiago, Chile, mcparra@hcuch.cl.
Abstract
BACKGROUNDS/AIMS: To assess the perinatal outcome of pregnancies with chorionic bump detected at the first trimester of pregnancy. METHODS: This was a nested case-control study of pregnancies with chorionic bump identified at the first trimester ultrasound that was performed from October 2014 and October 2016. The control group consisted of the following 5 unaffected pregnancies after each case. From the first trimester ultrasound, maternal and perinatal characteristics were obtained and stored in a dedicated database. The primary outcome was defined as the presence of an alive new-born. Secondary outcome was defined as the presence of a composite adverse obstetric outcome. RESULTS: Eleven first trimester pregnancies affected by a chorionic bump and 55 controls were identified. The primary outcome was observed in 72.7 and 89.1% of chorionic bump and controls respectively (p = 0.2). The secondary outcome was observed in 45.5% of pregnancies with a chorionic bump versus 12.7% in the unaffected group (p = 0.01). First trimester uterine artery Doppler demonstrated a non-significant trend to be higher in the chorionic bump group. CONCLUSIONS: The presence of a chorionic bump is associated with a significant higher risk of adverse perinatal outcome.
BACKGROUNDS/AIMS: To assess the perinatal outcome of pregnancies with chorionic bump detected at the first trimester of pregnancy. METHODS: This was a nested case-control study of pregnancies with chorionic bump identified at the first trimester ultrasound that was performed from October 2014 and October 2016. The control group consisted of the following 5 unaffected pregnancies after each case. From the first trimester ultrasound, maternal and perinatal characteristics were obtained and stored in a dedicated database. The primary outcome was defined as the presence of an alive new-born. Secondary outcome was defined as the presence of a composite adverse obstetric outcome. RESULTS: Eleven first trimester pregnancies affected by a chorionic bump and 55 controls were identified. The primary outcome was observed in 72.7 and 89.1% of chorionic bump and controls respectively (p = 0.2). The secondary outcome was observed in 45.5% of pregnancies with a chorionic bump versus 12.7% in the unaffected group (p = 0.01). First trimester uterine artery Doppler demonstrated a non-significant trend to be higher in the chorionic bump group. CONCLUSIONS: The presence of a chorionic bump is associated with a significant higher risk of adverse perinatal outcome.
Authors: Amman Yousaf; Ahmad Tayyab; Muhammad Sana Ullah Anil; Mohamed Mohamed Helmi Ahmed; Sana Sayed Hussein Badr Ahmed Ahmed; Amal Alobadli Journal: Cureus Date: 2020-11-14