| Literature DB >> 30391324 |
M Montero1, M Mir2, E Sulleiro3, J L Avalos Esquivel2, E García López4, D Molina-Morant5, I López Montesinos4, L Sorlí4, G Veliz Espinosa2, E Mounteis Oliva5, M Crespo2, I Monge6, J P Horcajada4, S Grau6, J Pascual2.
Abstract
There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.Entities:
Keywords: Benznidazole PK/PD; Benznidazole dose; Chagas disease; Chagoma; Kidney transplant recipient
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Year: 2018 PMID： 30391324 DOI： 10.1016/j.ijid.2018.10.014
Source DB: PubMed Journal: Int J Infect Dis ISSN： 1201-9712 Impact factor: 3.623