| Literature DB >> 30390740 |
Abstract
Pneumonia is an important cause of morbidity and mortality. However, pneumonia is an unusual outcome of respiratory infection. Most of the time, microbes in the lung can be controlled by a combination of constitutive and recruited defense mechanisms. Inflammation is a key component of recruited defenses. Variations in inflammation that influence pneumonia susceptibility and severity are considered here.Entities:
Keywords: Cytokines; Epithelial cells; Innate lymphocytes; Macrophages; NF-κB; Neutrophils; Pneumococcus; Resident memory cells
Mesh:
Year: 2018 PMID: 30390740 PMCID: PMC6221464 DOI: 10.1016/j.ccm.2018.07.002
Source DB: PubMed Journal: Clin Chest Med ISSN: 0272-5231 Impact factor: 2.878