Literature DB >> 3039048

Structure and variability of the a sequence in the genome of human cytomegalovirus (Towne strain).

E S Mocarski, A C Liu, R R Spaete.   

Abstract

We have defined the boundaries of the a sequence from human cytomegalovirus (CMV) strain Towne, characterized internal variability and determined the position of the cleavage site used to generate genomic termini. The cleavage site is positioned a fixed distance from two stretches of sequence homology that have been observed near the ends of many herpesvirus genomes. Unlike a comparable region in CMV (AD169), the CMV (Towne) a sequence has a relatively low level of variability within the a sequence and its structure is stable through repeated virus passage.

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Year:  1987        PMID： 3039048     DOI： 10.1099/0022-1317-68-8-2223

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  24 in total

1.  The ends on herpesvirus DNA replicative concatemers contain pac2 cis cleavage/packaging elements and their formation is controlled by terminal cis sequences.

Authors:  M A McVoy; D E Nixon; J K Hur; S P Adler
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

2.  Cloning of the full-length rhesus cytomegalovirus genome as an infectious and self-excisable bacterial artificial chromosome for analysis of viral pathogenesis.

Authors:  W L William Chang; Peter A Barry
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

3.  Rapid epidemiologic analysis of cytomegalovirus by using polymerase chain reaction amplification of the L-S junction region.

Authors:  D M Sokol; G J Demmler; G J Buffone
Journal:  J Clin Microbiol       Date:  1992-04       Impact factor: 5.948

4.  Sequences within the herpesvirus-conserved pac1 and pac2 motifs are required for cleavage and packaging of the murine cytomegalovirus genome.

Authors:  M A McVoy; D E Nixon; S P Adler; E S Mocarski
Journal:  J Virol       Date:  1998-01       Impact factor: 5.103

5.  Circularization and cleavage of guinea pig cytomegalovirus genomes.

Authors:  M A McVoy; D E Nixon; S P Adler
Journal:  J Virol       Date:  1997-06       Impact factor: 5.103

6.  A 128-base-pair sequence containing the pac1 and a presumed cryptic pac2 sequence includes cis elements sufficient to mediate efficient genome maturation of human cytomegalovirus.

Authors:  Jian Ben Wang; Michael A McVoy
Journal:  J Virol       Date:  2011-02-23       Impact factor: 5.103

7.  Impact of 2-bromo-5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole riboside and inhibitors of DNA, RNA, and protein synthesis on human cytomegalovirus genome maturation.

Authors:  Michael A McVoy; Daniel E Nixon
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

8.  Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle.

Authors:  Shih-Hsin Chiu; Meng-Chuan Wu; Chung-Chun Wu; Yu-Ching Chen; Su-Fang Lin; John T-A Hsu; Chung-Shi Yang; Ching-Hwa Tsai; Kenzo Takada; Mei-Ru Chen; Jen-Yang Chen
Journal:  J Virol       Date:  2014-02-19       Impact factor: 5.103

9.  Analysis of acquired human cytomegalovirus infections by polymerase chain reaction.

Authors:  J F Bale; M E O'Neil; S S Fowler; J R Murph
Journal:  J Clin Microbiol       Date:  1993-09       Impact factor: 5.948

10.  The herpes simplex virus type 1 (HSV-1) a sequence serves as a cleavage/packaging signal but does not drive recombinational genome isomerization when it is inserted into the HSV-2 genome.

Authors:  J R Smiley; C Lavery; M Howes
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103
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