Arvind Sabesan1, Benjamin L Gough2, Carinne Anderson3, Raafat Abdel-Misih4, Nicholas J Petrelli5, Joseph J Bennett6. 1. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: Arvind.Sabesan@christianacare.org. 2. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: Benjamin.L.Gough@christianacare.org. 3. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: carinne.wright@gmail.com. 4. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: RAbdel-Misih@christianacare.org. 5. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: NPetrelli@christianacare.org. 6. Helen F. Graham Cancer Center & Research Institute at Christiana Care Health System, Department of Surgery, 4701 Ogletown-Stanton Road Suite 4000, Newark, DE, USA, 19713. Electronic address: JoBennett@christianacare.org.
Abstract
BACKGROUND: We sought to evaluate the post-operative outcomes of patients undergoing pancreaticoduodenectomy at a high volume academic community cancer center. METHODS: A retrospective review was performed of patients undergoing pancreaticoduodenectomy over a 10-year period. RESULTS: Over 10 years, 213 patients underwent pancreaticoduodenectomy. Median age was 66y. Most patients had significant comorbidities (median ASA = 3) and were overweight (median BMI = 27). Median operative time and blood loss were 253 min and 500 ml, respectively. 160 (75%) out of 213 patients had a malignant lesion on final pathology. 121 (76%) out of 160 had R0 resection. Median lymph nodes harvested was 13. Overall incidence of DGE was 31% (67/213), with clinically significant DGE in 15% (32/213). Pancreatic leak rate was 18% (37/213), with clinically significant leaks in 10% (21/213). Median length of stay was 8 days. Grade 3/4 morbidity rate was 21% (44/206), and 30-day mortality was 2% (5/213). CONCLUSIONS: At a high volume academic community cancer center, pancreaticoduodenectomy can be performed with excellent outcomes on par with any academic center or university hospital.
BACKGROUND: We sought to evaluate the post-operative outcomes of patients undergoing pancreaticoduodenectomy at a high volume academic community cancer center. METHODS: A retrospective review was performed of patients undergoing pancreaticoduodenectomy over a 10-year period. RESULTS: Over 10 years, 213 patients underwent pancreaticoduodenectomy. Median age was 66y. Most patients had significant comorbidities (median ASA = 3) and were overweight (median BMI = 27). Median operative time and blood loss were 253 min and 500 ml, respectively. 160 (75%) out of 213 patients had a malignant lesion on final pathology. 121 (76%) out of 160 had R0 resection. Median lymph nodes harvested was 13. Overall incidence of DGE was 31% (67/213), with clinically significant DGE in 15% (32/213). Pancreatic leak rate was 18% (37/213), with clinically significant leaks in 10% (21/213). Median length of stay was 8 days. Grade 3/4 morbidity rate was 21% (44/206), and 30-day mortality was 2% (5/213). CONCLUSIONS: At a high volume academic community cancer center, pancreaticoduodenectomy can be performed with excellent outcomes on par with any academic center or university hospital.
Authors: Emil Sahlström; Johan Nilsson; Bobby Tingstedt; Magnus Bergenfeldt; Roland Andersson; Bodil Andersson Journal: Scand J Surg Date: 2020-04-17 Impact factor: 2.360