| Literature DB >> 3038824 |
P F Troke, R J Andrews, M S Marriott, K Richardson.
Abstract
The efficacy of fluconazole, a new bis-triazole antifungal agent, was compared with that of orally administered ketoconazole and parenterally administered amphotericin B against aspergillus and cryptococcus infections in mice. Fluconazole was 5-20-fold more active than ketoconazole against systemic aspergillosis and against systemic, intracranial and pulmonary cryptococcosis but was less active than amphotericin B.Entities:
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Year: 1987 PMID： 3038824 DOI： 10.1093/jac/19.5.663
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790